


Epitope-Specific Antibody Products
Overview
Epitope-specific antibodies are critical tools for current biomedical research, diagnosis, and therapy. These antibodies detect exact antigenic determinants on antigens, allowing for more tailored molecular interactions. Proudly, Creative Biolabs offers a wide range of epitope-specific antibody products and a tailored production service. Our solutions meet the vital requirement for high-quality, verified antibodies with excellent binding affinity and biological activity, allowing researchers to make significant improvements in their investigations.
Advantages of Epitope-Specific Antibodies
- Epitope-specific antibodies bind to precise antigenic determinants, ensuring high specificity and reduced off-target effects.
- By targeting specific epitopes, epitope-specific antibodies can detect low levels of antigens, improving diagnostic sensitivity.
- Epitope-specific antibodies can be designed to interfere with critical functions of target proteins, leading to more effective therapeutic interventions.
- Epitope-specific antibodies are widely used in diagnostics, therapeutics, research, and vaccine development.
- By minimizing exposure to non-immunogenic regions of the antigen, epitope-specific antibodies can reduce the risk of adverse immune responses.
Fig.1 Illustration depicting the interaction between the paratope of an antibody and its corresponding epitope on an antigen.1
Epitope-Specific Antibody Production Service at Creative Biolabs
Creative Biolabs is a leading provider of customized epitope-specific antibody production services, dedicated to delivering high-quality, validated antibodies for therapeutic development. Our comprehensive suite of services encompasses epitope identification and design, antibody production, characterization, and validation. By leveraging advanced technologies such as phage display, recombinant antibody engineering, and hybridoma technology, our experienced scientists generate antibodies with precise epitope specificity, superior affinity, and potent biological activity. Our belief in excellence, inventiveness, and customer satisfaction remains unchanged. Under rigorous quality control and characterization processes, we ensure that our clients receive the highest quality antibodies to accelerate their drug discovery and development programs.
Relevant Products and Services
In addition to our expertise in epitope-specific antibodies, our advanced antibody production platform enables the generation of antibodies with diverse functionalities, including agonist, antagonist, ADCC enhancing, etc. This versatility allows us to tailor antibody solutions to specific therapeutic or research needs, ensuring optimal performance across a wide range of applications.
Why Choose Us
- The experienced team ensures smooth antibody production processes.
- Customized antibody production process to meet your various needs.
- Operational specifications and technical facilities that meet industry regulatory standards.
- Rapid and efficient antibody product delivery.
Case Study
This study outlines an innovative method for the rapid production of epitope-directed monoclonal antibodies (mAbs) that enhance overall antibody quality and validation processes. Researchers developed a novel method for producing high-affinity monoclonal antibodies (mAbs) targeting specific epitopes on human ankyrin repeat domain 1 (hANKRD1). The integration of advanced microplates for miniaturized ELISA screening accelerated hybridoma identification and epitope mapping. Moreover, the resultant antibodies, which bind to different regions on hANKRD1, were validated through multiple techniques, including two-site ELISA, western blotting, and immunocytochemistry.
Fig.2 Antibody validation by ELISA assay.2
At Creative Biolabs, we leverage our extensive expertise and innovative technologies in antibody development to deliver exceptional solutions. Our expert research team is committed to creating customized antibody products that align with your unique research needs. We emphasize the adoption of advanced production methods that assure prompt delivery while keeping the highest quality requirements. For further information about our epitope-specific antibodies or personalized production services, please reach out to us for a customized consultation.
- Ledsgaard, Line, et al. "Antibody cross-reactivity in antivenom research." Toxins 10.10 (2018): 393. Distributed under Open Access License CC BY 4.0, without modification.
- Liew, Oi Wah, et al. "Epitope-directed monoclonal antibody production using a mixed antigen cocktail facilitates antibody characterization and validation." Communications Biology 4.1 (2021): 441. Distributed under Open Access License CC BY 4.0. The original image was modified by extracting and using part c, and the title was changed to "Antibody validation by ELISA assay".
- Recombinant Human Anti-C. botulinum botA Antibody (3D12) (EPAF-0045LC)
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- Species Reactivity: C. botulinum
- Type: IgG
- Application: ELISA, FuncS
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- Species Reactivity: C. botulinum A str. Hall
- Type: IgG1
- Application: ELISA, Neut
-
- Species Reactivity: HBV
- Type: IgG
- Application: Neut, WB
-
- Species Reactivity: HHV-5 strain AD169
- Type: IgG1
- Application: ELISA, Neut
- Recombinant Human Anti-Human F9 Antibody (10C12) (EPAF-0574CQ)
-
- Species Reactivity: Human
- Type: IgG1
- Application: ELISA
- Recombinant Mouse Anti-MARV GP Antibody (7E10) (EPAF-0808CQ)
-
- Species Reactivity: MARV
- Type: IgG
- Application: WB, IP
-
- Species Reactivity: C. botulinum
- Type: IgG
- Application: FC
- Recombinant Mouse Anti-Sheep Prnp Antibody (12B2) (EPAF-0079LC)
-
- Species Reactivity: Sheep, Cattle, Human
- Type: IgG
- Application: WB
-
- Species Reactivity: C. albicans
- Type: IgG3
- Application: ELISA
- Human Anti-F8 Recombinant Antibody (clone BO2C11) (EPAF-0611LC)
-
- Species Reactivity: Human
- Type: Human IgG4
- Application: ELISA
- Recombinant Mouse Anti-PERV-A TM Antibody (7C4) (EPAF-0780LC)
-
- Species Reactivity: PERV-A
- Type: IgG
- Application: BL, ELISA
-
- Species Reactivity: C. albicans
- Type: IgG3
- Application: ELISA
- Recombinant Mouse Anti-H1N1 M2 Antibody (14C2) (EPAF-1107LC)
-
- Species Reactivity: Influenza A virus H1N1
- Application: ELISA
-
- Species Reactivity: P. falciparum
- Application: ELISA
- Recombinant Mouse Anti-PRNP Antibody (6H4) (EPAF-1421LC)
-
- Species Reactivity: Cattle
- Application: IF
- Recombinant Mouse Anti-PRNP Antibody (12F10) (EPAF-1423LC)
-
- Species Reactivity: Human, Sheep
- Application: IF
- Recombinant Mouse Anti-PRNP Antibody (94B4) (EPAF-1490LC)
-
- Species Reactivity: Human, Sheep
- Application: WB
- Recombinant Human Anti-C. botulinum botA Antibody (3F10) (EPAF-0108CQ)
-
- Species Reactivity: C. botulinum
- Type: IgG
- Application: ELISA
-
- Species Reactivity: HBV
- Type: IgG1
- Application: Inhib
-
- Species Reactivity: IAV (A/X-31(H3N2))
- Type: IgG
- Application: Neut
-
- Species Reactivity: P. falciparum NF54
- Type: IgG
- Application: Inhib
-
- Species Reactivity: P. yoelii yoelii
- Type: IgG2b
- Application: ELISA
-
- Species Reactivity: P. yoelii yoelii
- Type: IgG
- Application: WB
- Recombinant Mouse Anti-P.vivax CSP Antibody (4E8) (EPAF-0992CQ)
-
- Species Reactivity: P. vivax
- Type: IgG
- Application: Inhib
- Recombinant Mouse Anti-P.vivax GAM1 Antibody (A12) (EPAF-0993CQ)
-
- Species Reactivity: P. vivax
- Type: IgG
- Application: WB, ELISA
- Recombinant Mouse Anti-P.vivax Pvs25 Antibody (2A8) (EPAF-0994CQ)
-
- Species Reactivity: P. vivax
- Type: IgG1
- Application: ELISA
- Recombinant Bovine Anti-P. haemolytica plpE Antibody (EPAF-0995CQ)
-
- Species Reactivity: P. haemolytica
- Type: IgG
- Application: WB
-
- Species Reactivity: PhMV
- Type: IgG
- Application: ELISA, WB
-
- Species Reactivity: PhMV
- Type: IgG
- Application: ELISA, WB
-
- Species Reactivity: PhMV
- Type: IgG
- Application: Inhib, WB, ELISA
-
- Species Reactivity: PMTV
- Type: IgG
- Application: ELISA
-
- Species Reactivity: PMTV
- Type: IgG1
- Application: ELISA
-
- Species Reactivity: PMTV
- Type: IgG1
- Application: ELISA
-
- Species Reactivity: PMTV
- Type: IgG1
- Application: ELISA
-
- Species Reactivity: PMTV
- Type: IgG2a
- Application: ELISA
-
- Species Reactivity: PMTV
- Type: IgG3
- Application: EM, ELISA
-
- Species Reactivity: Poliovirus type 3
- Type: IgG
- Application: ELISA, Neut
-
- Species Reactivity: Porcine rotavirus (STRAIN YM)
- Type: IgG
- Application: IP
-
- Species Reactivity: Porcine rotavirus (STRAIN YM)
- Type: IgG
- Application: Neut
-
- Species Reactivity: Porcine rotavirus strain A253
- Type: IgG
- Application: Neut
- Recombinant Mouse Anti-PPV Polyprotein Antibody (scFv2A) (EPAF-1009CQ)
-
- Species Reactivity: PPV
- Type: IgG
- Application: WB, Inhib
-
- Species Reactivity: PPV (strain W)
- Type: IgG
- Application: ELISA
-
- Species Reactivity: PPV (strain W)
- Type: IgG
- Application: ELISA
-
- Species Reactivity: PPV (strain W)
- Type: IgG
- Application: ELISA
-
- Species Reactivity: PPV (strain W)
- Type: IgG
- Application: ELISA
-
- Species Reactivity: PPV (strain W)
- Type: IgG
- Application: ELISA
-
- Species Reactivity: PPV (strain W)
- Type: IgG
- Application: ELISA
-
- Species Reactivity: PPV (strain W)
- Type: IgG
- Application: ELISA
-
- Species Reactivity: PPV (strain W)
- Type: IgG
- Application: ELISA
- Recombinant Mouse Anti-PRRSV GP3 Antibody (31A2) (EPAF-1018CQ)
-
- Species Reactivity: PRRSV
- Type: IgG
- Application: ELISA
- Recombinant Mouse Anti-PRRSV GP3 Antibody (32D4) (EPAF-1019CQ)
-
- Species Reactivity: PRRSV
- Type: IgG
- Application: ELISA
- Recombinant Mouse Anti-PRRSV GP3 Antibody (32H7) (EPAF-1020CQ)
-
- Species Reactivity: PRRSV
- Type: IgG
- Application: ELISA
- Recombinant Mouse Anti-PRRSV GP5 Antibody (P10/a46) (EPAF-1021CQ)
-
- Species Reactivity: PRRSV
- Type: IgG
- Application: ELISA
- Recombinant Mouse Anti-PRRSV Nsp2 Antibody (D3A4) (EPAF-1022CQ)
-
- Species Reactivity: PRRSV
- Type: IgG2a
- Application: ELISA, WB, IHC
- Recombinant Mouse Anti-PRRSV Nsp2 Antibody (E5F8) (EPAF-1024CQ)
-
- Species Reactivity: PRRSV
- Type: IgG2a
- Application: ELISA, WB, IHC
- Recombinant Mouse Anti-PRRSV Nsp2 Antibody (E8A8) (EPAF-1025CQ)
-
- Species Reactivity: PRRSV
- Type: IgG2a
- Application: ELISA, WB, IHC
- Recombinant Mouse Anti-PRRSV Nsp2 Antibody (A6D3) (EPAF-1026CQ)
-
- Species Reactivity: PRRSV
- Type: IgG2a
- Application: WB, ELISA, IHC
- Recombinant Mouse Anti-PRRSV ORF 7 Antibody (1D2) (EPAF-1027CQ)
-
- Species Reactivity: PRRSV
- Type: IgG2b
- Application: IP
- Recombinant Mouse Anti-PRRSV ORF 7 Antibody (ISU15B) (EPAF-1028CQ)
-
- Species Reactivity: PRRSV
- Type: IgG1
- Application: IP
- Recombinant Mouse Anti-PRRSV ORF 7 Antibody (K9-3) (EPAF-1029CQ)
-
- Species Reactivity: PRRSV
- Type: IgG
- Application: IP
-
- Species Reactivity: PRRSV
- Type: IgG
- Application: IP
- Recombinant Mouse Anti-PRRSV ORF3 Antibody (31G11) (EPAF-1031CQ)
-
- Species Reactivity: PRRSV
- Type: IgG
- Application: ELISA
- Recombinant Mouse Anti-PRRSV ORF3 Antibody (32B12) (EPAF-1032CQ)
-
- Species Reactivity: PRRSV
- Type: IgG
- Application: ELISA
-
- Species Reactivity: PRRSV
- Type: IgG2a
- Application: WB, ELISA, IHC
- Recombinant Mouse Anti-PRRSV CH-1a ORF7 Antibody (N1A2) (EPAF-1034CQ)
-
- Species Reactivity: PRRSV CH-1a
- Type: IgG
- Application: ELISA
- Recombinant Mouse Anti-PRRSV CH-1a ORF7 Antibody (N1H11) (EPAF-1035CQ)
-
- Species Reactivity: PRRSV CH-1a
- Type: IgG
- Application: ELISA
- Recombinant Mouse Anti-PRRSV CH-1a ORF7 Antibody (N2F7) (EPAF-1036CQ)
-
- Species Reactivity: PRRSV CH-1a
- Type: IgG
- Application: ELISA
- Recombinant Mouse Anti-PRRSV CH-1a ORF7 Antibody (N2H7) (EPAF-1037CQ)
-
- Species Reactivity: PRRSV CH-1a
- Type: IgG
- Application: ELISA
-
- Species Reactivity: P. porphyriacus
- Type: IgG1
- Application: Inhib
-
- Species Reactivity: P. porphyriacus
- Type: IgG1
- Application: Inhib
- Recombinant Mouse Anti-PUUV N Antibody (EPAF-1044CQ)
-
- Species Reactivity: PUUV
- Type: IgG
- Application: ELISA
-
- Species Reactivity: PUUV sotkamo/v-2969/81
- Type: IgG
- Application: ELISA
-
- Species Reactivity: PUUV sotkamo/v-2969/81
- Type: IgG
- Application: ELISA, IF, WB
- Recombinant Human Anti-RABV G Antibody (CR4098) (EPAF-1047CQ)
-
- Species Reactivity: RABV
- Type: IgG1
- Application: ELISA
- Recombinant Human Anti-RABV G Antibody (F21) (EPAF-1048CQ)
-
- Species Reactivity: RABV
- Type: IgG
- Application: ELISA, Neut
- Recombinant Human Anti-RABV G Antibody (CR57) (EPAF-1051CQ)
-
- Species Reactivity: RABV
- Type: IgG1
- Application: Neut
- Recombinant Mouse Anti-Rat Itga1 Antibody (huAQC2) (EPAF-1066CQ)
-
- Species Reactivity: Rat
- Type: IgG1
- Application: ELISA
- Recombinant Human Anti-S. aureus entB Antibody (EPAF-1095CQ)
-
- Species Reactivity: S. aureus
- Type: IgG
- Application: WB
-
- Species Reactivity: S. oralis
- Type: IgG
- Application: ELISA
-
- Species Reactivity: S. oralis
- Type: IgG
- Application: ELISA
-
- Species Reactivity: S. oralis
- Type: IgG
- Application: ELISA
-
- Species Reactivity: S. pneumoniae
- Type: IgG1
- Application: ELISA, Inhib, WB
-
- Species Reactivity: S. pneumoniae
- Type: IgG1
- Application: Neut, WB, FC
-
- Species Reactivity: S. pyogenes serotype M5
- Type: IgG
- Application: Neut
-
- Species Reactivity: S. pyogenes serotype M5
- Type: IgG
- Application: WB
-
- Species Reactivity: S. pyogenes serotype M5
- Type: IgG
- Application: WB
- Recombinant Human Anti-SARS-CoV S Antibody (m396) (EPAF-1139CQ)
-
- Species Reactivity: SARS-CoV
- Type: IgG1
- Application: ELISA
- Recombinant Human Anti-SARS-CoV Urbani S Antibody (201) (EPAF-1162CQ)
-
- Species Reactivity: SARS-CoV Urbani
- Type: IgG
- Application: FC
- Recombinant Mouse Anti-SLEV E Antibody (6B6C-1) (EPAF-1201CQ)
-
- Species Reactivity: SLEV
- Type: IgG
- Application: ELISA
- Recombinant Mouse Anti-T. cruzi TcP2beta Antibody (17.2) (EPAF-1258CQ)
-
- Species Reactivity: T. cruzi
- Type: IgG1
- Application: WB, EM
- Recombinant Human Anti-T. cruzi B13 antigen Antibody (EPAF-1259CQ)
-
- Species Reactivity: T. cruzi
- Type: IgG
- Application: Inhib
- Recombinant Mouse Anti-T. gondii p30 Antibody (4F11E12) (EPAF-1260CQ)
-
- Species Reactivity: T. gondii
- Type: IgG2a
- Application: ELISA
- Recombinant Human Anti-T.gondii GRA2 Antibody (EPAF-1263CQ)
-
- Species Reactivity: T. gondii
- Application: WB
- Recombinant Human Anti-T.gondii GRA 1 Antibody (EPAF-1265CQ)
-
- Species Reactivity: T. gondii
- Type: IgG
- Application: ELISA
- Recombinant Mouse Anti-WNV Env Antibody (4G2) (EPAF-1334CQ)
-
- Species Reactivity: WNV
- Type: IgG
- Application: ELISA
- Recombinant Mouse Anti-WNV Env Antibody (6B6C-1) (EPAF-1335CQ)
-
- Species Reactivity: WNV
- Type: IgG
- Application: ELISA
-
- Species Reactivity: YFV 17D/Tiantan
- Type: IgG
- Application: IP, Neut
- Recombinant Mouse Anti-YFV 17D/Tiantan E Antibody (2C9) (EPAF-1340CQ)
-
- Species Reactivity: YFV 17D/Tiantan
- Type: IgG
- Application: Neut
-
- Type: IgG1
- Application: ELISA
-
- Type: IgG1
- Application: ELISA
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