H-2 IAb/Mouse Ovalbumin (AAHAEINEA) MHC Tetramer
CAT#: MHC-YF805
This product is a MHC tetramer of biotinylated peptide/MHC complex composed Ovalbumin-derived peptide of AAHAEINEA sequence covering 329-337 and H-2 IAb molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Specifications
- Allele
- H-2 IAb
- Class
- Class II
- MHC Species
- Mouse
- Antigen
- Ovalbumin
- Antigen Species
- Chicken
- Peptide
- AAHAEINEA
- Range
- 329-337
- Application
- FCM
Target
- Antigen Introduction
- Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up approximately 55% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein.
- Alternative Names
- OVA; Ovalbumin
- Gene ID
- 396058
- UniProt ID
- P01012
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Robust Data From This Tetramer
Using this product, we've obtained robust data that directly impacts our understanding of T cell dynamics. The tetramer's quality has consistently produced high-fidelity results in flow cytometry assays.
Great for Immune Response Studies
We've leveraged this tetramer to investigate immune responses in different experimental settings, and it hasn't disappointed. Its robust performance in flow cytometry has pinpointed T cell populations effectively, contributing to a deeper understanding of immune mechanisms.
Q&As
-
What is the primary application of the H-2 IAb/Mouse Ovalbumin MHC Tetramer?
A: This tetramer is primarily used for flow cytometry analysis to identify and quantify antigen-specific CD8 T cells. Its precise application helps researchers study immune responses in various experimental setups, making it invaluable for immunological research.
-
Why is the ovalbumin-derived peptide sequence 329-337 chosen?
A: The 329-337 sequence is a well-characterized epitope for MHC and T cell receptor interaction studies, providing robust and reliable data in immunological assays.
View the frequently asked questions answered by Creative Biolabs Support.
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