H-2 Kb/Mouse Survivin (MFFCFKEL) MHC Tetramer (CAT#: MHC-YF952)
This product is a MHC tetramer of biotinylated peptide/MHC complex composed Survivin-derived peptide of MFFCFKEL sequence and H-2 Kb molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Specific Inquiry
Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Specifications
- Allele
- H-2 Kb
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- Survivin
- Antigen Species
- Human
- Peptide
- MFFCFKEL
- Application
- FCM
Target
- Antigen Introduction
- This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
- Alternative Names
- API4; EPR-1
- Gene ID
- 332
- UniProt ID
- O15392
Downloads
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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