H-2Db/Human WT1 (CMTWNQMNL) MHC Tetramer
CAT#: MHC-CN1396
Specifications
- Allele
- H-2Db
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- WT1
- Antigen Species
- Human
- Peptide
- CMTWNQMNL
- Conjugate
- Unconjugated
- Application
- FCM, IHC
Target
- Antigen Introduction
- This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Mar 2015]
- Alternative Names
- Wilms Tumor 1; WT33; Wilms Tumor Protein; NPHS4; WIT-2; WAGR; AWT1; GUD;
- Gene ID
- 7490
- UniProt ID
- P19544
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Datasheet
MSDS
COA
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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| AGTO-G065R | Anti-WT1 immunotoxin 6F-H2 (IgG)-RTA | Cytotoxicity assay, Function study |
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| MOR-3886 | Rabbit Anti-WT1 Recombinant Antibody (clone DS3886AB) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| MRO-1597-CN | Rabbit Anti-WT1 Recombinant Antibody (clone CBACN-584) | WB, IF, IHC, FC | Rabbit IgG |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| VS-0525-XY7945 | Anti-WT1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7946 | Anti-Mouse WT1 Immunohistochemistry Kit | IHC |
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