H-2Kb/Human muFAP alpha (SDYYFSWL) MHC Pentamer (CAT#: MHC-YF573)

MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed muFAP alpha-derived peptide of SDYYFSWL sequence covering 289-296 and H-2Kb molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.

Specific Inquiry Online Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Specifications

  • Allele
  • H-2Kb
  • Class
  • Class I
  • MHC Species
  • Mouse
  • Antigen
  • muFAP alpha
  • Antigen Species
  • Human
  • Peptide
  • SDYYFSWL
  • Range
  • 289-296
  • Conjugate
  • Unlabeled, Biotin, R-PE, APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
  • Alternative Names
  • Fibroblast Activation Protein Alpha; Seprase; 170 KDa Melanoma Membrane-Bound Gelatinase; Gelatine Degradation Protease FAP; Integral Membrane Serine Protease; Post-Proline Cleaving Enzyme; Surface-Expressed Protease; Dipeptidyl Peptidase FAP; FAPalpha; SIMP;

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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