H-2Kd/Influenza A virus Haemagglutinin (IYSTVASSL) MHC Pentamer (CAT#: MHC-YC213)

MHC multimers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a Pentamer of peptide/MHC complex with IAV-derived peptide of IYSTVASSL sequence covering 533-541 and H-2Kd molecule. The peptide/MHC pentamer provided here is unlabeled or fluorescent labeled such as Biotin, R-PE, APC. And all of them are available in 50, 150 or 500 tests.


Specific Inquiry
  • Size:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Allele
  • H-2Kd
  • Class
  • Class I
  • Antigen
  • Influenza A virus Haemagglutinin
  • Antigen Species
  • IAV
  • Peptide
  • IYSTVASSL
  • Range
  • 533-541
  • Conjugate
  • Unlabeled, Biotin, R-PE, APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • HA binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
  • Alternative Names
  • FLUAVs4gp1

Downloads

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See other products for "IAV HA"

Human Antibody

CAT Product Name Application Type
TAB-H33 Anti-IAV HA Recombinant Antibody (Firivumab) FC, IP, ELISA, Neut, FuncS, IF, ICC IgG1 - kappa
TAB-027ML Anti-IAV HA Recombinant Antibody (Gedivumab) ELISA, IHC, FC, IP, IF, FuncS IgG1, κ
TAB-438CQ Anti-IAV HA Recombinant Antibody (Navivumab) ELISA, IHC, FC, IP, IF, BL IgG1, κ

Epitope-Specific Antibody

CAT Product Name Application Type
EPAF-0652CQ Recombinant Mouse Anti-IAV HA Antibody (pSAN13.4.1) ELISA IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-027ML Afuco™ Anti-IAV HA ADCC Recombinant Antibody (Gedivumab), ADCC Enhanced ELISA, IHC, FC, IP, IF, FuncS ADCC enhanced antibody
AFC-TAB-438CQ Afuco™ Anti-IAV HA ADCC Recombinant Antibody (Navivumab), ADCC Enhanced ELISA, IHC, FC, IP, IF, BL ADCC enhanced antibody
AFC-TAB-H33 Afuco™ Anti-IAV HA ADCC Recombinant Antibody (Firivumab), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF ADCC enhanced antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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