Human Anti-CD4 (clone TRX1) scFv-Fc Chimera

Name: Human Anti-CD4 (clone TRX1) scFv-Fc Chimera
SKU: VS-0325-FY64
Rating: 5 (1 reviews)

CAT#: VS-0325-FY64

Anti-CD4 scFv-Fc antibodies are engineered proteins that combine single-chain variable fragments (scFvs) targeting the CD4 antigen with an Fc region, enhancing their stability and efficacy. They are primarily used in immunological research, therapy for autoimmune diseases, and as potential tools in cancer immunotherapy. These antibodies can modulate T cell responses, making them useful in various applications including flow cytometry, immunoprecipitation, and targeted drug delivery. Their versatility and specificity position them as valuable assets in both basic and translational research.
The TRX1 antibody should be administered at a level that saturates all CD4 receptors in the primate being treated, implying a high affinity to ensure effective binding and occupancy of the CD4 receptors.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-251 MG

Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/11/if_selected.jpg

RNA Expression Figure 2 RNA cell line category: Group enriched (HEL, HL-60, NB-4, THP-1, U-937)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000010610-CD4

❮

❯

Specifications

Host Species
Human

Type
Human IgG1, scFv-Fc

Specificity
Human CD4

Species Reactivity
Human

Clone
TRX1

Applications
ELISA

Related Disease
Autoimmune disease

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
Please refer to the vial label for the specific concentration.

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Shipping
Ice packs

Target

Alternative Names
CD4 Molecule; T-Cell Surface Glycoprotein CD4; T-Cell Surface Antigen T4/Leu-3; CD4 Antigen (P55); CD4 Receptor; CD4 Antigen; CD4mut

Gene ID
920

UniProt ID
P01730

Long Name
CD4 Molecule

Cellular Localization
Cell membrane; Membrane

Function
CD4 is a glycoprotein found on the surface of T helper cells, a subset of white blood cells. Its primary function is to act as a co-receptor that assists the T cell receptor (TCR) in recognizing antigens presented by antigen-presenting cells (APCs) on MHC class II molecules. This interaction is crucial for initiating an immune response, particularly in coordinating the activation of other immune cells, like B cells and cytotoxic T cells, through the release of cytokines. CD4 also serves as the primary receptor for the human immunodeficiency virus (HIV).

REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS

Inquiry

Navs

Customer Review

There are currently no Customer reviews or questions for VS-0325-FY64. Click the button above to contact us or submit your feedback about this product.

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Related Diseases

Primary Immunodeficiency

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - VS-0325-FY64.pdf

MSDS

MSDS - VS-0325-FY64.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Isotype Control

CAT
Product Name

Secondary Antibody

CAT
Product Name

See other products for "Clone TRX1"

CAT
Product Name

See other products for "CD4"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
TAB-039	Anti-Human CD4 Recombinant Antibody (Zanolimumab)	Neut, ELISA, IF, IP, FuncS, FC, IHC	IgG1 - kappa

CAT	Product Name	Application	Type
TAB-260	Anti-Human CD4 Recombinant Antibody (Tregalizumab)	WB, ELISA, FC, IP, FuncS, IF, Neut	IgG1 - kappa
TAB-161LC	Anti-Human CD4 Recombinant Antibody (gOKT4A-4)	ELISA	Humanized antibody
TAB-168LC	Anti-Human CD4 Recombinant Antibody (TRX1)	ELISA	Humanized antibody
TAB-171LC	Human Anti-CD4 Recombinant Antibody (TAB-171LC)	ELISA, FC, SPR	Humanized antibody
TAB-172LC	Human Anti-CD4 Recombinant Antibody (TAB-172LC)	ELISA, Inhib	Human IgG

CAT	Product Name	Application	Type
AGTO-G078E	Anti-CD4 immunotoxin M-T151 (IgG)-PE	Cytotoxicity assay, Function study
AGTO-G078R	Anti-CD4 immunotoxin M-T151 (IgG)-RTA	Cytotoxicity assay, Function study

CAT	Product Name	Application	Type
PFBL-423	Human Anti-CD4 Recombinant Antibody (clone 576); Fab Fragment	WB, ELISA, FuncS	Human Fab
PFBL-424	Human Anti-CD4 Recombinant Antibody (clone Hu5A8); Fab Fragment	Block, Neut	Human Fab
HPAB-0135CQ-F(E)	Human Anti-CD4 Recombinant Antibody; Fab Fragment (HPAB-0135CQ-F(E))	ELISA, FuncS	Human Fab
HPAB-0136CQ-F(E)	Mouse Anti-CD4 Recombinant Antibody; Fab Fragment (HPAB-0136CQ-F(E))	ELISA, FuncS	Mouse Fab
HPAB-0137CQ-F(E)	Mouse Anti-CD4 Recombinant Antibody (clone RIB 5/2); Fab Fragment	IHC, FC	Mouse Fab

CAT	Product Name	Application	Type
TAB-160LC-S(P)	Anti-Human CD4 Recombinant Antibody scFv Fragment (OKT4A)	ELISA
TAB-166LC-S(P)	Anti-Human CD4 Recombinant Antibody scFv Fragment (M-T412)	ELISA
TAB-169LC-S(P)	Rat Anti-CD4 Recombinant Antibody; scFv Fragment (TAB-169LC-S(P))	ELISA, SPR	Rat scFv
TAB-173LC-S(P)	Anti-Human CD4 Recombinant Antibody scFv Fragment (IgA F425-Alg8)	ELISA
TAB-174LC-S(P)	Mouse Anti-CD4 Recombinant Antibody; scFv Fragment (TAB-174LC-S(P))	ELISA, FC, IH	Mouse scFv

CAT	Product Name	Application	Type
TAB-162LC-S(P)	Anti-Human CD4 Recombinant Antibody scFv Fragment	ELISA	Chimeric antibody (mouse/human)
TAB-164LC-S(P)	Monkey Anti-CD4 Recombinant Antibody; scFv Fragment (TAB-164LC-S(P))	FC, SPR, ELISA	Monkey scFv
TAB-165LC-S(P)	Monkey Anti-CD4 Recombinant Antibody; scFv Fragment (TAB-165LC-S(P))	FC, SPR, ELISA	Monkey scFv
TAB-167LC-S(P)	Anti-Human CD4 Recombinant Antibody scFv Fragment (cM-T412)	ELISA	Chimeric antibody (mouse/human)
TAB-170LC-S(P)	Rat Anti-CD4 Recombinant Antibody; scFv Fragment (TAB-170LC-S(P))	ELISA, SPR	Rat scFv

CAT	Product Name	Application	Type
Gly-025LC	Recombinant Anti-Human CD4 Antibody (Fab glycosylation)	ELISA	Humanized antibody

CAT	Product Name	Application	Type
NEUT-351CQ	Mouse Anti-CD4 Recombinant Antibody (clone 10C12)	ELISA, WB, IF, Block	Mouse IgG1
NEUT-352CQ	Mouse Anti-CD4 Recombinant Antibody (clone 13B8.2)	Block, ELISA, FC, IHC-Fr, WB	Mouse IgG1, κ
NEUT-355CQ	Mouse Anti-CD4 Recombinant Antibody (clone RPA-T4)	FC, CyTOF, Block, IHC	Mouse IgG1, κ
NEUT-357CQ	Rat Anti-CD4 Recombinant Antibody (clone MAB0810)	Block, Depletion, Stim	Rat IgG2b
NEUT-358CQ	Rat Anti-CD4 Recombinant Antibody (clone RM4-5)	FC, CyTOF, Depletion, Block, IHC	Rat IgG2a, κ

CAT	Product Name	Application	Type
NEUT-353CQ	Mouse Anti-CD4 Recombinant Antibody (clone CBL976)	FC, Neut, IF, IHC	Mouse IgG1, κ
NEUT-354CQ	Recombinant Mouse Anti-CD4 Antibody (CT-4)	Neut, FC, IHC, IHC-Fr, IHC-P, IP	IgG1, κ
NEUT-356CQ	Mouse Anti-CD4 Recombinant Antibody (clone 3-4F4)	Neut, FC, IHC, IHC-Fr, IP, ICC	Mouse IgG1, κ

CAT	Product Name	Application	Type
MOR-0560	Hi-Affi™ Rabbit Anti-CD4 Recombinant Antibody (clone DS560AB)	IHC-P	Rabbit IgG

CAT	Product Name	Application	Type
HPAB-0302LY-S(P)	Human Anti-CD4 Recombinant Antibody (clone TNX-355); scfv Fragment	ELISA	Humanized scfv
HPAB-0303LY-S(P)	Human Anti-CD4 Recombinant Antibody (clone G4H); scfv Fragment	ELISA	Humanized scfv
HPAB-0304LY-S(P)	Human Anti-CD4 Recombinant Antibody (clone G4D); scfv Fragment	ELISA	Humanized scfv
HPAB-0305LY-S(P)	Human Anti-CD4 Recombinant Antibody (clone MV1); scfv Fragment	ELISA	Humanized scfv
HPAB-2059LY-S(P)	Mouse Anti-CD4 Recombinant Antibody; scFv Fragment (HPAB-2059LY-S(P))	FC	Mouse scfv

CAT	Product Name	Application	Type
MRO-0303-CN	Rabbit Anti-CD4 Recombinant Antibody (clone CBACN-117)	WB, IF, IHC	Rabbit IgG
HPAB-0957WJ	Human Anti-CD4 Recombinant Antibody (clone 4-91)	ELISA	Human IgG
FAMAB-1058CQ	Human Anti-CD4 Recombinant Antibody (clone DB81)	Inhib, FC	Human IgG1
FAMAB-1059CQ	Mouse Anti-CD4 Recombinant Antibody (clone 8A5)	WB, ELISA, IF	Mouse IgG1
FAMAB-1060CQ	Rat Anti-CD4 Recombinant Antibody (clone YNB46.1.8 (Campath-9H))	FC, IHC, IHC-Fr	Rat IgG1

CAT	Product Name	Application	Type
AFC-TAB-039	Afuco™ Anti-CD4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-039)	Neut, ELISA, IF, IP, FuncS, FC	ADCC enhanced antibody
AFC-TAB-164	Afuco™ Anti-CD4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-164)	FuncS, IF, Neut, ELISA, FC	ADCC enhanced antibody
AFC-TAB-260	Afuco™ Anti-CD4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-260)	ELISA, FC, IP, FuncS, IF	ADCC enhanced antibody
AFC-TAB-171	Afuco™ Anti-CD4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-171)	FuncS, IF, Neut, ELISA, FC, IP	ADCC enhanced antibody
AFC-TAB-107	Afuco™ Anti-CD4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-107)	IF, IP, Neut, FuncS, ELISA, FC	ADCC enhanced antibody

CAT	Product Name	Application	Type
VS-0724-YC759	AbPlus™ Anti-Cd4 Magnetic Beads (VS-0724-YC759)	IP, Protein Purification

CAT	Product Name	Application	Type
VS-0924-YC114	Rat Anti-CD4 Recombinant Antibody Hexamer (VS-0924-YC114), CDC Enhanced	ELISA, FC, CDC	Antibody hexamer
VS-0924-YC115	Human Anti-CD4 Recombinant Antibody Hexamer (VS-0924-YC115), CDC Enhanced	ELISA, FC, ADCC, CDC, SPR	Antibody hexamer
VS-0924-YC116	Mouse Anti-CD4 Recombinant Antibody Hexamer (VS-0924-YC116), CDC Enhanced	WB, ELISA, IF, CDC	Antibody hexamer

CAT	Product Name	Application	Type
VS-1024-XY95	Mouse Anti-NHP CD4 Recombinant Antibody (clone RIV7)	IF, FC	Mouse IgG2a, kappa

CAT	Product Name	Application	Type
VS-0225-XY48	CytoStream™ Mouse Anti-CD4 Recombinant Antibody (clone OKT4)	FC	Mouse IgG2b, kappa
VS-0225-XY49	CytoStream™ Mouse Anti-CD4 Recombinant Antibody (clone OX-35)	FC	Mouse IgG2a, kappa
VS-0225-XY50	CytoStream™ Rat Anti-CD4 Recombinant Antibody (clone RM4-4)	FC	Rat IgG2b, kappa
VS-0225-XY51	CytoStream™ Mouse Anti-CD4 Recombinant Antibody (clone KEN-4)	FC, Block, IHC, IP	Mouse IgG2a, kappa

CAT	Product Name	Application	Type
VS-0425-YC755	Recombinant Anti-CD4 Vesicular Antibody, EV Displayed (VS-0425-YC755)	ELISA, FC, Neut, Cell-uptake

CAT	Product Name	Application
VS-0525-XY1178	Anti-CD4 Immunohistochemistry Kit	IHC
VS-0525-XY1179	Anti-Mouse CD4 Immunohistochemistry Kit	IHC
VS-0525-XY1180	Anti-Human CD4 Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0525-YC204	Recombinant Anti-CD4 (Domain 1 x Domain 2) Biparatopic Antibody, Tandem scFv	ELISA, FC, ICC, IF, IP, Neut	Tandem scFv

Specific Inquiry

Size:

Conjugation:

Endotoxin:

Purity:

Formats:

Isotype Switching:

Fc Engineering:

Modalities:

Add to compare

Request
Custom Production

See Our Custom Production in Action

Figure 1 Anti-HBV Recombinant Antibody (TAB-147) in SDS-PAGE

Download the full case study

Popular Products

Figure 2 Mouse Anti-CD3E Recombinant Antibody (clone UCHT1); Fab Fragment (DrMAB-989) in HPLC

Mouse Anti-CD3E Recombinant Antibody (clone UCHT1); Fab Fragment (CAT# DrMAB-989)
Application: FC, Cyt, Stim, PP, Agonist

Figure 5 Anti-Human TNFSF11 Antibody (TAB-H18) in DB

Human Anti-TNFSF11 Recombinant Antibody (TAB-H18) (CAT# TAB-H18)
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC

Figure 5 Anti-Human IL-6 Recombinant Antibody (TAB-253) in HPLC

Anti-Human IL-6 Recombinant Antibody (Olokizumab) (CAT# TAB-253)
Application: WB, ELISA, FC, IP, FuncS, IF, Neut

Figure 3 Anti-ErbB2 Antibody (TAB-053) in Dot Blot

Anti-Human ERBB2 Recombinant Antibody (TAB-053) (CAT# TAB-053)
Application: FuncS, IF, Neut, ELISA, FC, IP, WB

Figure 5 Anti-Human EGFR Recombinant Antibody (Modotuximab) (TAB-H49) in DB

Anti-Human EGFR Recombinant Antibody (Modotuximab) (CAT# TAB-H49)
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC

Figure 3 Anti-Human SPP1 Antibody (TAB-582CL) in DB

Anti-Human SPP1 Recombinant Antibody (ASK8007) (CAT# TAB-582CL)
Application:

Figure 2 Anti-C3b Antibody (PABL-420) in HPLC

Human Anti-C3b Recombinant Antibody (clone S77) (CAT# PABL-420)
Application: FuncS, Inhib, IP, ELISA

Figure 5 Human Anti-IL13 Recombinant Antibody (clone CNTO607) (PABW-170) in SEC-HPLC

Human Anti-IL13 Recombinant Antibody (clone CNTO607) (CAT# PABW-170)
Application: ELISA, WB, Neut

Figure 5 Human Anti-ASGR Recombinant Antibody (TAB-1013CLV) in ELISA

Human Anti-ASGR Recombinant Antibody (TAB-1013CLV) (CAT# TAB-1013CLV)
Application: FC, FRET, Internalization

Figure 4 Rat Anti-CD38 Recombinant Antibody (NEUT-349CQ) in ELISA

Rat Anti-CD38 Recombinant Antibody (clone NIMR-5) (CAT# NEUT-349CQ)
Application: Neut, FC, IHC-Fr, IP, BA

Figure 2 Human CRCP Recombinant Antibody (TAB-426CQ) in HPLC

Human Anti-CRCP Recombinant Antibody (TAB-426CQ) (CAT# TAB-426CQ)
Application: ELISA, IHC, FC, IP, IF, Inhib

Figure 3 Anti-Human FCGRT Antibody (TAB-450CQ) in ELISA

Anti-Human FCGRT Recombinant Antibody (TAB-450CQ) (CAT# TAB-450CQ)
Application: ELISA, IHC, FC, IP, IF, FuncS

Figure 3 Rat Anti-IL18 Recombinant Antibody (HPAB-0067-YC-S(P)) in ELISA

Rat Anti-IL18 Recombinant Antibody (clone 2C10); scFv Fragment (CAT# HPAB-0067-YC-S(P))
Application: Neut

Figure 2 Recombinant Human Anti-C. botulinum A str. Hall botA Antibody (S25 chimera) (EPAF-0119CQ) in WB

Recombinant Human Anti-C. botulinum A str. Hall botA Antibody (S25 chimera) (CAT# EPAF-0119CQ)
Application: ELISA, Neut

Figure 3 Anti-Human IAV HA Recombinant Antibody (MOB-074LC) in ELISA

Human Anti-EPCAM Recombinant Antibody (clone ING-1) (CAT# MOB-074LC)
Application: ELISA, FuncS

Figure 2 Human Anti-GRP78 Recombinant Antibody (HPAB-0366LY) in HPLC

Human Anti-GRP78 Recombinant Antibody (clone SAM-6) (CAT# HPAB-0366LY)
Application: WB, FC, IF, Inhib, ELISA, IHC

Figure 2 Anti-TMEM30A Recombinant Antibody (PABL-712CQ) in HPLC

Human Anti-TMEM30A Recombinant Antibody (PABL-712CQ) (CAT# PABL-712CQ)
Application: ELISA, FC

Figure 2 Mouse Anti-MCAM Recombinant Antibody (HPAB-0031-YJ) in WB

Mouse Anti-MCAM Recombinant Antibody (clone AA98) (CAT# HPAB-0031-YJ)
Application: ELISA, FC, Inhib, IHC-Fr, WB, IP

Figure 8 Anti-CD19 scFv (FMC63) Recombinant Antibody (HPAB-0440-YJ)-Fc silenced in WB

Mouse Anti-CD19 scFv (FMC63) Recombinant Antibody (HPAB-0440-YJ) (CAT# HPAB-0440-YJ)
Application: ELISA, FC, WB, Inhib, IHC

Figure 1. Recombinant Rabbit Anti-VPS4A Antibody (clone R01-9H9) in WB.

Recombinant Rabbit Anti-VPS4A Antibody (clone R01-9H9) (CAT# VS3-FY1548)
Application: WB, IHC-Fr, IHC-P, ICC, IF

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.