Human Anti-CD7 scFv-Fc Chimera (VS-0325-FY126)
CAT#: VS-0325-FY126
The Anti-CD7 scFv-Fc antibody is a novel immunotherapeutic agent designed for targeted cancer therapy. This molecule combines the specificity of a single-chain variable fragment (scFv) targeting the CD7 antigen with a modified Fc region of an IgG1 antibody. This dual mechanism aims to enhance antibody-dependent cell-mediated cytotoxicity (ADCC) and improve the therapeutic efficacy against CD7-expressing cancers.
Gene Expression
Normal Tissue
Figure 1 Colon
Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/39079/133943_A_8_3.jpg
Normal Tissue
Figure 2 Spleen
Cells in red pulp
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Cells in white pulp
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/39079/133943_B_7_4.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (Hep G2, JURKAT, MOLT-4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000173762-CD7
❮
❯
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human CD7
- Species Reactivity
- Human
- Applications
- ADCC
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- CD7 Molecule; T-Cell Leukemia Antigen; T-Cell Surface Antigen Leu-9; T-Cell Antigen CD7; CD7 Antigen (P41); P41 Protein
- Gene ID
- 924
- UniProt ID
- P09564
- Long Name
- CD7 Molecule
- Cellular Localization
- Membrane
- Protein Refseq
- NP_006128.1
- Function
- CD7 is a transmembrane glycoprotein expressed on the surface of T lymphocytes and natural killer (NK) cells. It functions as a co-stimulatory molecule, participating in T cell activation and signaling. CD7 also plays a role in cell adhesion and migration, contributing to the trafficking of lymphocytes within the immune system. Its expression is valuable in the diagnosis of certain hematologic malignancies, particularly T-cell acute lymphoblastic leukemia (T-ALL).
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0325-FY126. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "CD7"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-183-F(E) | Recombinant Anti-human CD7 Antibody Fab Fragment | IP, Neut, FuncS | Fab |
| MHH-183-F(E) | Recombinant Human Anti-human CD7 Antibody Fab Fragment | Neut, WB, FuncS | Fab |
| FAMAB-0049CQ-F(E) | Human Anti-CD7 Recombinant Antibody (clone CHT2); Fab Fragment | IHC, FC, Block, IF | Chimeric (mouse/human) Fab |
| FAMAB-0050CQ-F(E) | Mouse Anti-CD7 Recombinant Antibody (clone RFT2); Fab Fragment | IHC, FC, Block, IF | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-183-S(P) | Recombinant Anti-human CD7 Antibody scFv Fragment | ELISA, WB, FC, FuncS | scFv |
| MHH-183-S(P) | Recombinant Human Anti-human CD7 Antibody scFv Fragment | ELISA, WB, IF, FuncS | scFv |
| FAMAB-0049CQ-S(P) | Mouse Anti-CD7 Recombinant Antibody (clone CHT2); scFv Fragment | IHC, FC, Block, IF | Mouse scFv |
| FAMAB-0050CQ-S(P) | Mouse Anti-CD7 Recombinant Antibody (clone RFT2); scFv Fragment | IHC, FC, Block, IF | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G011E | Anti-CD7 immunotoxin TH-69 (scFv)-PE | Cytotoxicity assay, Function study | |
| AGTO-G011R | Anti-CD7 immunotoxin TH-69 (scFv)-RTA | Cytotoxicity assay, Function study | |
| AGTO-G011S | Anti-CD7 immunotoxin TH-69 (scFv)-Sap | Cytotoxicity assay, Function study | |
| AGTO-G082E | Anti-CD7 immunotoxin (IgG)-PE | Cytotoxicity assay, Function study | |
| AGTO-G082R | Anti-CD7 immunotoxin (IgG)-RTA | Cytotoxicity assay, Function study |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-001LC-VHH | Anti-Human CD7 Recombinant Antibody | IF, ELISA | Single domain antibody |
| HPAB-0265-YJ-VHH | Recombinant Camel Anti-CD7 Single Domain Antibody (HPAB-0265-YJ-VHH) | ELISA, FC, IF | Camel VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0274MZ | Recombinant Mouse Anti-Human CD7 Molecule Antibody (clone DBC.38) | IHC | Mouse antibody |
| FAMAB-0049CQ | Human Anti-CD7 Recombinant Antibody (clone CHT2) | IHC, FC, Block, IF | Chimeric (mouse/human) IgG1, κ |
| FAMAB-0050CQ | Mouse Anti-CD7 Recombinant Antibody (clone RFT2) | IHC, FC, Block, IF | Mouse IgG1, κ |
| FN-020CQ | Mouse Anti-CD7 Recombinant Antibody (clone 3A1E) | FC, FuncS | Mouse IgG2b |
| VS3-FY1677 | Rabbit Anti-CD7 Recombinant Antibody (clone R03-8G3) | WB, IHC-Fr, IHC-P, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0577 | Hi-Affi™ Rabbit Anti-CD7 Recombinant Antibody (clone DS577AB) | ICC, IHC-P, IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC714 | AbPlus™ Anti-CD7 Magnetic Beads (VS-0724-YC714) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY68 | CytoStream™ Mouse Anti-CD7 Recombinant Antibody (VS-0225-XY68) | FC | Mouse IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY372 | Anti-CD7 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1214 | Anti-Human CD7 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC728 | Recombinant Anti-CD7 Vesicular Antibody, EV Displayed (VS-0425-YC728) | ELISA, FC, Cell-uptake |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
-2.png)
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: ELISA, FC, IF, WB
Application: ELISA, FC, Inhib
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
