Human Anti-CLEC12A scFv-Fc Chimera (VS-0325-FY10)

Name: Human Anti-CLEC12A scFv-Fc Chimera (VS-0325-FY10)
SKU: VS-0325-FY10
Rating: 5 (1 reviews)

CAT#: VS-0325-FY10

The Anti-CLEC12A scFv-Fc Antibody targets the CLEC12A molecule, which is involved in immune cell recognition. It provides high specificity and can be used to study the role of CLEC12A in immune responses. This antibody is suitable for use in immunology and cell biology research.

Gene Expression

Normal Tissue Figure 1 Colon

Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48515/114818_A_7_3.jpg

Normal Tissue Figure 2 Kidney

Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48515/114818_A_7_5.jpg

Normal Tissue Figure 3 High expression in bone marrow

Hematopoietic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48515/114818_B_5_4.jpg

RNA Expression Figure 4 RNA cell line category: Group enriched (HL-60, U-937)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000172322-CLEC12A

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Specifications

Host Species
Human

Type
Human IgG1, scFv-Fc

Specificity
Human CLEC12A

Species Reactivity
Human

Applications
ELISA, Flow Cytometry

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
Please refer to the vial label for the specific concentration.

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Shipping
Ice packs

Target

Alternative Names
C-Type Lectin Domain Family 12 Member A; Myeloid Inhibitory C-Type Lectin-Like Receptor; Dendritic Cell-Associated Lectin 2; DCAL-2; CLL-1; CLL1; MICL

Gene ID
160364

UniProt ID
Q5QGZ9

Long Name
C-Type Lectin Domain Family 12 Member A

Cellular Localization
Cell membrane

Post Translation Modifications
Highly N-glycosylated.
Glycosylation varies between cell types.
Glycosylation at Asn80, Asn88, Asn98, Asn105, Asn165, and Asn210
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 3 sites

Protein Refseq
XP_005253381.1; XP_006719096.1; XP_006719098.2; XP_006719099.2; XP_011518872.1

Function
Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - VS-0325-FY10.pdf

MSDS

MSDS - VS-0325-FY10.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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Isotype Control

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Secondary Antibody

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TAB-525LC-S(P)	Mouse Anti-CLEC12A Recombinant Antibody; scFv Fragment (TAB-525LC-S(P))	ELISA	Mouse scFv
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HPAB-2073LY-F(E)	Mouse Anti-CLEC12A Recombinant Antibody; Fab Fragment (HPAB-2073LY-F(E))	ELISA, FC	Mouse Fab
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HPAB-2075LY-F(E)	Mouse Anti-CLEC12A Recombinant Antibody; Fab Fragment (HPAB-2075LY-F(E))	ELISA, FC	Mouse Fab
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