Human Anti-CLEC12A scFv-Fc Chimera (VS-0325-FY10) (CAT#: VS-0325-FY10)
The Anti-CLEC12A scFv-Fc Antibody targets the CLEC12A molecule, which is involved in immune cell recognition. It provides high specificity and can be used to study the role of CLEC12A in immune responses. This antibody is suitable for use in immunology and cell biology research.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Colon
(Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48515/114818_A_7_3.jpg
(Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48515/114818_A_7_3.jpg
Figure 2 Kidney
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48515/114818_A_7_5.jpg
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48515/114818_A_7_5.jpg
Figure 3 High expression in bone marrow
(Hematopoietic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48515/114818_B_5_4.jpg
(Hematopoietic cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48515/114818_B_5_4.jpg
Figure 4 RNA cell line category: Group enriched (HL-60, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000172322-CLEC12A
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000172322-CLEC12A
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human CLEC12A
- Species Reactivity
- Human
- Applications
- ELISA, Flow Cytometry
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- C-Type Lectin Domain Family 12 Member A; Myeloid Inhibitory C-Type Lectin-Like Receptor; Dendritic Cell-Associated Lectin 2; DCAL-2; CLL-1; CLL1; MICL
- Gene ID
- 160364
- UniProt ID
- Q5QGZ9
- Long Name
- C-Type Lectin Domain Family 12 Member A
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Highly N-glycosylated.
Glycosylation varies between cell types.
Glycosylation at Asn80, Asn88, Asn98, Asn105, Asn165, and Asn210
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 3 sites
- Protein Refseq
- XP_005253381.1; XP_006719096.1; XP_006719098.2; XP_006719099.2; XP_011518872.1
- Function
- Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Flow Cytometry (FC) related Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-512LC | Human Anti-CLEC12A Recombinant Antibody (TAB-512LC) | FuncS | Chimeric (mouse/human) IgG |
| TAB-523LC | Human Anti-CLEC12A Recombinant Antibody (TAB-523LC) | ELISA | Chimeric (mouse/human) IgG |
| TAB-524LC | Human Anti-CLEC12A Recombinant Antibody (TAB-524LC) | ELISA | Chimeric (mouse/human) IgG |
| TAB-525LC | Human Anti-CLEC12A Recombinant Antibody (TAB-525LC) | Cyt, FuncS | Chimeric (mouse/human) IgG |
| TAB-526LC | Human Anti-CLEC12A Recombinant Antibody (TAB-526LC) | Cyt | Chimeric antibody (mouse/human) |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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