Human Anti-CRP scFv-Fc Chimera (VS-0125-FY49) (CAT#: VS-0125-FY49)
This scFv-Fc fusion protein designed to specifically bind to C-reactive protein (CRP), which plays an important role in inflammatory responses. The scFv part consists of single-chain antibody fragments capable of effectively recognizing and binding to CRP, thereby enhancing the affinity of the antibody. Through this specific binding, the fusion protein assists in monitoring and assessing inflammatory states, improving the accuracy of disease diagnosis. In the future, this engineered antibody fragment may provide new insights and methods for the treatment and management of inflammation-related diseases.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line EFO-21
(Immunofluorescent staining of human cell line EFO-21 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27367/1842_C4_62_selected.jpg
(Immunofluorescent staining of human cell line EFO-21 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27367/1842_C4_62_selected.jpg
Figure 2 IHC staining of human liver
(Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27367/ihc_selected.jpg
(Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27367/ihc_selected.jpg
Figure 3 IHC staining of human blood vessel
(Immunohistochemical staining of human blood vessel shows distinct positivity of plasma.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5036/ihc_selected.jpg
(Immunohistochemical staining of human blood vessel shows distinct positivity of plasma.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5036/ihc_selected.jpg
Figure 4 Immunofluorescent staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27367/395_F9_1_red_green.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27367/395_F9_1_red_green.jpg
Figure 5 Immunofluorescent staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27367/399_F9_1_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27367/399_F9_1_red_green.jpg
Figure 6 Liver
(Hepatocytes
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5036/14071_A_8_4.jpg
(Hepatocytes
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5036/14071_A_8_4.jpg
Figure 7 RNA cell line category: Cell line enhanced (EFO-21, HDLM-2, U-2 OS, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000132693-CRP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000132693-CRP
Figure 7 RNA cell line category: Cell line enhanced (EFO-21, HDLM-2, U-2 OS, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000132693-CRP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000132693-CRP
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Species Reactivity
- Human
- Applications
- ELISA
- Related Disease
- Inflammation
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Stabilizer
- No Stabilizers
- Sterility
- 0.2 μM filtered
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- C-Reactive Protein; C-Reactive Protein, Pentraxin-Related; Pentraxin 1; PTX1
- Gene ID
- 1401
- UniProt ID
- P02741
- Cellular Localization
- Secreted
- Post Translation Modifications
- Modification sites at PhosphoSitePlus
Modification sites at neXtProt
- Protein Refseq
- NP_000558.2; NP_001315986.1
- Function
- Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CRP"
Select a product category from the dropdown menu below to view related products.
Please select product type
Fab Antibody Products
Chicken IgY Antibody Products
Rabbit Monoclonal Antibody Products
ScFv Antibody Products
IgG Antibody Products
Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-1013 | Mouse Anti-CRP Recombinant Antibody (clone YC027); Fab Fragment | ELISA, LMNX, LFIA | Mouse Fab |
| HPAB-0213-FY-F(E) | Mouse Anti-CRP Recombinant Antibody Fab Fragment (HPAB-0213-FY-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0214-FY-F(E) | Mouse Anti-CRP Recombinant Antibody Fab Fragment (HPAB-0214-FY-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-M0039-YC-F(E) | Mouse Anti-CRP Recombinant Antibody (clone P24); Fab Fragment | ELISA | Mouse Fab |
| HPAB-M0040-YC-F(E) | Mouse Anti-CRP Recombinant Antibody (clone P03); Fab Fragment | ELISA | Mouse Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS-0125-FY49. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: WB, ELISA, IP, FC, FuncS, Neut, IF
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: WB, IHC, FC, Cyt, ELISA
Application: WB, IF, FuncS
-1-1.png)
Application: ELISA
Application: SPR, Inhib, FuncS
Application: Inhib, FC, WB
Application: ELISA, FC, FuncS
Application: ELISA, FuncS, RIA, IP, IF, IHC, IA, Block
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
