Human Anti-CSF2 (clone MSB-0010628) scFv-Fc Chimera (CAT#: VS-0425-FY98)
This fusion protein targets CSF2 (GM-CSF), a cytokine that stimulates the growth and differentiation of granulocytes and macrophages. By modulating CSF2 activity, it can influence immune cell function, with potential applications in treating hematological malignancies and inflammatory conditions.
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57404/1703_H9_1_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57404/1703_H9_1_selected.jpg
Figure 2 RNA cell line category: Cell line enriched (BJ hTERT+)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164400-CSF2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164400-CSF2
Figure 2 RNA cell line category: Cell line enriched (BJ hTERT+)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164400-CSF2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164400-CSF2
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human CSF2
- Species Reactivity
- Human
- Clone
- MSB-0010628
- Applications
- Inhibition
- Related Disease
- Diagnostic Agents; Inflammation; Autoimmune disease
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The optimal dilution concentration is determined by the experiment.
Target
- Alternative Names
- Colony Stimulating Factor 2; Molgramostin; Colony Stimulating Factor 2 (Granulocyte-Macrophage); GMCSF; CSF
- Gene ID
- 1437
- UniProt ID
- P04141
- Long Name
- Colony Stimulating Factor 2
- Sequence Similarities
- Belongs to the GM-CSF family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- Glycosylation at Ser22, Ser24, Ser26, Thr27, Asn44, and Asn54
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 8 sites, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_000749.2
- Function
- Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
Related Resources
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-478 | Human Anti-CSF2 Recombinant Antibody (clone MB007); Fab Fragment | Neut | Human Fab |
| HPAB-0431-CN-F(E) | Human Anti-CSF2 Recombinant Antibody; Fab Fragment (HPAB-0431-CN-F(E)) | ELISA, FC, Neut | Human Fab |
| PFBC-337 | Human Anti-CSF2 Recombinant Antibody (clone F1); Fab Fragment | ELISA, FC, Neut | Human Fab |
| PFBC-338 | Mouse Anti-CSF2 Recombinant Antibody (clone 4D4); Fab Fragment | ELISA, FC, Neut | Mouse Fab |
| PABJ-0112-F(E) | Human Anti-CSF2 Recombinant Antibody Fab Fragment (PABJ-0112-F(E)) | ELISA, Neut | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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