Recombinant Human Anti-GAD2 Soluble TCR () (KIH)
CAT#: VS-0622-YF6366
Human TCR recognizes GAD2 peptide (NMYAMMIARFKMFPEVKEKG) in the context of HLA-DR. Soluble TCR is expressed with Knob-in-hole (KIH) strategy (scTCR-hIgG Knob, scTCR-hIgG Hole). Please note that the activity is not guaranteed.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous nuclear
Neuropil
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78177/163309_B_9_5.jpg
Normal Tissue
Figure 2 Pancreas
Pancreatic endocrine cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78177/163309_A_3_3.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enriched (SCLC-21H)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000136750-GAD2
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Specifications
- Host Species
- Human
- Target
- GAD2
- Species Reactivity
- Human
- Epitope
- NMYAMMIARFKMFPEVKEKG
- MHC
- HLA-DR
- Type
- Soluble TCR (KIH)
- Related Disease
- Pancreatic cancer
- TCR Expression Strategy
- KIH strategy: scTCR-human IgG Knob and scTCR-human IgG Hole can form heterodimer based on Knob-in-hole (KIH) strategy. The soluble TCR contains single chain TCR. With this KIH antibody production strategy, VL/VH will be replaced with Valpha-linker-Vbeta (single chain TCR).
Target
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Related Diseases
Maturity Onset Diabetes of the Young
Downloadable Resources
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Datasheet
MSDS
COA
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|---|---|---|---|
| MOB-1147z | Mouse Anti-GAD2 Recombinant Antibody (clone 28G2) | WB, ELISA, FC | Mouse IgG1 |
| HPAB-1982-FY | Human Anti-GAD2 Recombinant Antibody (clone b78) | Inhib | Human IgG1, λ |
| VS1-YJ63 | Mouse Anti-GAD2 Recombinant Antibody (clone 144) | WB, FC, IP | Mouse IgG1 |
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| VS3-WK1834 | Recombinant Rabbit Anti-GAD2 Capture Antibody (clone R46-7A-6) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1389 | Hi-Affi™ Rabbit Anti-GAD2 Recombinant Antibody (clone DS1389AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0697 | PE-DRB1*04:01/Human GAD2 (IAFTSEHSHFSLK) MHC Tetramer | FCM, IHC | |
| MHC-CN0698 | APC-DRB1*04:01/Human GAD2 (IAFTSEHSHFSLK) MHC Tetramer | FCM, IHC | |
| MHC-CN0699 | FITC-DRB1*04:01/Human GAD2 (IAFTSEHSHFSLK) MHC Tetramer | FCM, IHC | |
| MHC-CN0700 | DRB1*04:01/Human GAD2 (IAFTSEHSHFSLK) MHC Tetramer | FCM, IHC | |
| MHC-CN0701 | PE-DRB1*04:01/Human GAD2 (NFIRMVISNPAAT) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1982-FY-F(E) | Human Anti-GAD2 Recombinant Antibody (clone b78); Fab Fragment | Inhib | Human Fab, λ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1982-FY-S(P) | Human Anti-GAD2 Recombinant Antibody (clone b78); scFv Fragment | Inhib | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF030 | DRB1*04:01/Human GAD65 (IAFTSEHSHFSLK) MHC Monomer | MHC Multimer | |
| MHC-YF033 | DRB1*04:01/Human GAD65 (NFIRMVISNPAAT) MHC Monomer | MHC Multimer | |
| MHC-YF034 | DRB1*04:01/Human GAD65 (DVMNILLQYVVKSFDRSTKV) MHC Monomer | MHC Multimer | |
| MHC-YF035 | DRB1*04:01/Human GAD65 (KGMAALPRLIAFTSEHSHFS) MHC Monomer | MHC Multimer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC793 | AbPlus™ Anti-GAD2 Magnetic Beads (VS-0724-YC793) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2716 | Anti-GAD2 Immunohistochemistry Kit | IHC |
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