Recombinant Human Anti-GAD2 Soluble TCR () (ZIP-Fos/ZIP-Jun)
CAT#: VS-0622-YF950
Human TCR recognizes GAD2 peptide (NMYAMMIARFKMFPEVKEKG) in the context of HLA-DR. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (). Please note that the activity is not guaranteed.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous nuclear
Neuropil
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78177/163309_B_9_5.jpg
Normal Tissue
Figure 2 Pancreas
Pancreatic endocrine cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78177/163309_A_3_3.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enriched (SCLC-21H)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000136750-GAD2
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Specifications
- Host Species
- Human
- Target
- GAD2
- Species Reactivity
- Human
- Epitope
- NMYAMMIARFKMFPEVKEKG
- MHC
- HLA-DR
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- Related Disease
- Pancreatic cancer
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
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Related Diseases
Maturity Onset Diabetes of the Young
Downloadable Resources
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Datasheet
MSDS
COA
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