Human Anti-GLP1R (clone h38C2) scFv-Fc Chimera
CAT#: VS-0425-FY111
This scFv-Fc fusion protein targets GLP1R (Glucagon-like peptide 1 receptor), a receptor involved in glucose metabolism and insulin secretion. By modulating GLP1R activity, it can influence glucose homeostasis and is being explored for its potential use in diabetes management.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (NTERA-2, SCLC-21H)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000112164-GLP1R
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Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human GLP1R
- Species Reactivity
- Human
- Clone
- h38C2
- Applications
- Immunoassay
- Related Disease
- Cardiovascular disease; nephropathy; neuropathy; and retinopathy
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The optimal dilution concentration is determined by the experiment.
Target
- Alternative Names
- Glucagon Like Peptide 1 Receptor; Glucagon-Like Peptide 1 Receptor; GLP-1 Receptor; GLP-1-R; GLP-1R; Seven Transmembrane Helix Receptor; GLP1 Receptor; GLP-1
- Gene ID
- 2740
- UniProt ID
- P43220
- Long Name
- Glucagon Like Peptide 1 Receptor
- Sequence Similarities
- Belongs to the G-protein coupled receptor 2 family.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- N-glycosylation enhances cell surface expression and lengthens receptor half-life by preventing degradation in the ER.
Glycosylation at Asn63, Asn82, and Asn115
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 3 sites
- Protein Refseq
- NP_002053.3
- Function
- G-protein coupled receptor for glucagon-like peptide 1 (GLP-1).
Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone h38C2"
- CAT
- Product Name
See other products for "GLP1R"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2540z | Mouse Anti-GLP1R Recombinant Antibody (MOB-2540z) | ELISA, WB, IP, IF, IHC, FC | Mouse IgG2b, κ |
| HPAB-1530-FY | Human Anti-GLP1R Recombinant Antibody (HPAB-1530-FY) | ELISA, Inhib, IHC | Human IgG1, κ |
| HPAB-1531-FY | Mouse Anti-GLP1R Recombinant Antibody (HPAB-1531-FY) | ELISA, Inhib, IHC | Mouse IgG2a |
| VS1-YJ72 | Chicken Anti-Glp1r Antibody (VS-0722-YJ72) | ELISA | Chicken IgY |
| VS4-WK197 | Human Anti-GLP1R Recombinant Antibody (clone 7H7) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2540z-F(E) | Recombinant Anti-Human GLP1R Antibody Fab Fragment | ELISA, FuncS | Fab |
| HPAB-0384-YC-F(E) | Human Anti-GLP1R Recombinant Antibody; Fab Fragment (HPAB-0384-YC-F(E)) | ELISA, FC, FuncS | Human Fab |
| HPAB-0385-YC-F(E) | Mouse Anti-GLP1R Recombinant Antibody (clone m38C2); Fab Fragment | FuncS | Mouse Fab |
| HPAB-1530-FY-S(P) | Human Anti-GLP1R Recombinant Antibody; scFv Fragment (HPAB-1530-FY-S(P)) | ELISA, Inhib, IHC | Human scFv |
| HPAB-1531-FY-S(P) | Mouse Anti-GLP1R Recombinant Antibody; scFv Fragment (HPAB-1531-FY-S(P)) | ELISA, Inhib, IHC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2540z-S(P) | Recombinant Anti-Human GLP1R Antibody scFv Fragment | WB, FC, FuncS | scFv |
| HPAB-0384-YC-S(P) | Human Anti-GLP1R Recombinant Antibody; scFv Fragment (HPAB-0384-YC-S(P)) | ELISA, FC, FuncS | Human scFv |
| HPAB-0385-YC-S(P) | Mouse Anti-GLP1R Recombinant Antibody (clone m38C2); scFv Fragment | FuncS | Mouse scFv |
| HPAB-1530-FY-F(E) | Human Anti-GLP1R Recombinant Antibody; Fab Fragment (HPAB-1530-FY-F(E)) | ELISA, Inhib, IHC | Human Fab |
| HPAB-1531-FY-F(E) | Mouse Anti-GLP1R Recombinant Antibody; Fab Fragment (HPAB-1531-FY-F(E)) | ELISA, Inhib, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-145CT | Mouse Anti-GLP1R Recombinant Antibody (TAB-145CT) | ELISA, FC | Mouse IgG1 |
| TAB-145CT-S(P) | Mouse Anti-GLP1R Recombinant Antibody; scFv Fragment (TAB-145CT-S(P)) | ELISA, FC | Mouse scFv |
| TAB-145CT-F(E) | Mouse Anti-GLP1R Recombinant Antibody; Fab Fragment (TAB-145CT-F(E)) | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-031CN | Human Anti-GLP1R Recombinant Antibody (clone 5A10) | ELISA, FC | Human IgG |
| NS-031CN-F(E) | Human Anti-GLP1R Recombinant Antibody (clone 5A10); Fab Fragment | ELISA, FC | Human Fab |
| NS-031CN-S(P) | Human Anti-GLP1R Recombinant Antibody (clone 5A10); scFv Fragment | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC452 | CytoStream™ Rabbit Anti-Glp1r Polyclonal Antibody (VS13-YC452) | WB, ELISA, IHC-P, IHC-Fr, FC, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC612 | Recombinant Anti-GLP1R Vesicular Antibody, EV Displayed (VS-0425-YC612) | Block, ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2829 | Anti-GLP1R Immunohistochemistry Kit | IHC | |
| VS-0525-XY2830 | Anti-Mouse GLP1R Immunohistochemistry Kit | IHC |
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