Human Anti-GLP1R (clone h38C2) scFv-Fc Chimera (CAT#: VS-0425-FY111)
This scFv-Fc fusion protein targets GLP1R (Glucagon-like peptide 1 receptor), a receptor involved in glucose metabolism and insulin secretion. By modulating GLP1R activity, it can influence glucose homeostasis and is being explored for its potential use in diabetes management.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (NTERA-2, SCLC-21H)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000112164-GLP1R
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000112164-GLP1R
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human GLP1R
- Species Reactivity
- Human
- Clone
- h38C2
- Applications
- Immunoassay
- Related Disease
- Cardiovascular disease; nephropathy; neuropathy; and retinopathy
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The optimal dilution concentration is determined by the experiment.
Target
- Alternative Names
- Glucagon Like Peptide 1 Receptor; Glucagon-Like Peptide 1 Receptor; GLP-1 Receptor; GLP-1-R; GLP-1R; Seven Transmembrane Helix Receptor; GLP1 Receptor; GLP-1
- Gene ID
- 2740
- UniProt ID
- P43220
- Long Name
- Glucagon Like Peptide 1 Receptor
- Sequence Similarities
- Belongs to the G-protein coupled receptor 2 family.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- N-glycosylation enhances cell surface expression and lengthens receptor half-life by preventing degradation in the ER.
Glycosylation at Asn63, Asn82, and Asn115
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 3 sites
- Protein Refseq
- NP_002053.3
- Function
- G-protein coupled receptor for glucagon-like peptide 1 (GLP-1).
Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone h38C2"
See other products for "GLP1R"
Select a product category from the dropdown menu below to view related products.
Please select product type
Mouse Antibody Products
IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
Neuroscience Antibody Products
Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-145CT | Mouse Anti-GLP1R Recombinant Antibody (TAB-145CT) | ELISA, FC | Mouse IgG1 |
| TAB-145CT-S(P) | Mouse Anti-GLP1R Recombinant Antibody; scFv Fragment (TAB-145CT-S(P)) | ELISA, FC | Mouse scFv |
| TAB-145CT-F(E) | Mouse Anti-GLP1R Recombinant Antibody; Fab Fragment (TAB-145CT-F(E)) | ELISA, FC | Mouse Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS-0425-FY111. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
-1-1.png)
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: Neut, ELISA, FuncS
Application: ELISA
Application: Neut, FC, IHC-Fr, IP, BA
Application: ELISA, IHC, FC, IP, IF, FuncS
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
