Human Anti-HIV-1 Env (clone A7) scFv-Fc Chimera
CAT#: VS-0125-FY6
The A7 scFv-Fc antibody plays a crucial role in neutralizing HIV-1, making it an important tool in the development of vaccines and therapies against HIV. Its unique structure allows it to effectively bind to the virus, neutralizing its infectivity and preventing the virus from entering host cells. Furthermore, ongoing research is focused on optimizing this antibody for enhanced potency and broader neutralization capabilities, which could significantly improve the outcomes of HIV treatment and vaccination strategies. Additionally, exploring its mechanism of action may reveal new insights into the immune response against HIV, ultimately aiding in the fight against this global epidemic.
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Species Reactivity
- Human immunodeficiency virus (HIV)
- Clone
- A7
- Applications
- Neutralization
- Related Disease
- HIV infection
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Stabilizer
- No Stabilizers
- Sterility
- 0.2 μM filtered
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The A7 scFv-Fc antibodies have the potential to specifically target and bind to distinct epitopes on the HIV-1 envelope glycoprotein gp120. This targeting ability may play a crucial role in neutralizing HIV-1, making these antibodies a valuable asset in the development of vaccines and therapeutic strategies to combat HIV.
Target
- Alternative Names
- HIV-1 env glycoprotein; Human immunodeficiency virus-1 Glycoprotein
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
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CAT | Product Name | Application | Type |
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CAT | Product Name | Application | Type |
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PFBL-137 | Human Anti-HIV-1 Env Recombinant Antibody (clone PGT124); Fab Fragment | WB, Neut, FuncS | Human Fab |
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MRO-2809CQ | Human Anti-HIV-1 Env Recombinant Antibody (clone N03B11) | ELISA | Humanized IgM |
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VS-0125-FY69 | Human Anti-HIV-1 Env (clone PGT121) scFv-Fc Chimera | Neut | Human IgG1, scFv-Fc |
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VS-0625-XY21 | Monkey Anti-HIV-1 Env Vaccinal Antibody (VS-0625-XY21) | ELISA | Monkey IgG |
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VS-0625-XY25 | Human Anti-HIV-1 Env Vaccinal Antibody (VS-0625-XY25) | ELISA | Human IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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