Human Anti-HIV-1 Env (clone PGT121) scFv-Fc Chimera (CAT#: VS-0125-FY69)
The anti-HIV-1 scFv-Fc antibody targets the envelope protein of HIV-1, specifically the epitope crucial for the virus's ability to invade host cells. By binding to specific HIV-1 antigens, these antibodies can neutralize the virus and prevent it from infecting cells. The main role of the anti-scFv-Fc antibody is to neutralize HIV-1, effectively blocking its capacity to infect host cells. In comparison to traditional full-length IgG antibodies, the single-chain design addresses issues related to the mismatch between heavy and light chains, improving expression efficiency and usability. Moreover, the scFv-Fc structure facilitates universal binding to the Fc fragment, which helps extend its half-life in the body.
Specific Inquiry
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Species Reactivity
- Human immunodeficiency virus (HIV)
- Clone
- PGT121
- Applications
- Neutralization
- Related Disease
- HIV infection
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Stabilizer
- No Stabilizers
- Sterility
- 0.2 μM filtered
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The anti-scFv-Fc antibody has the potential to effectively neutralize the HIV-1 virus, thereby preventing it from infecting host cells. Its single-chain structure design may address the challenge of heavy and light chain mismatch typically associated with traditional full-length IgG, which can enhance antibody expression efficiency and broaden its applications. Furthermore, the scFv-Fc format is capable of binding universally to the Fc fragment, potentially prolonging its half-life in the body.
Target
- Alternative Names
- HIV-1 env glycoprotein; Human immunodeficiency virus-1 Glycoprotein
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "HIV-1 Env"
Select a product category from the dropdown menu below to view related products.
Please select product type
Fab Antibody Products
Single Domain Antibody Products
IgG Antibody Products
ScFv Antibody Products
MHC Tetramer Products for Virology
IgM Antibody Products
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-474-F(E) | Recombinant Anti-HIV-1 Env Antibody Fab Fragment | IP, FuncS | Fab |
| MHH-474-F(E) | Recombinant Human Anti-HIV-1 Env Antibody Fab Fragment | ELISA, WB, FuncS | Fab |
| PFBL-137 | Human Anti-HIV-1 Env Recombinant Antibody (clone PGT124); Fab Fragment | WB, Neut, FuncS | Human Fab |
| PFBL-141 | Human Anti-HIV-1 Env Recombinant Antibody Fab Fragment (PFBL-141) | WB, ELISA, Neut, FuncS | Human Fab |
| PFBL-143 | Human Anti-HIV-1 Env Recombinant Antibody (clone 9H+3L); Fab Fragment | WB, ELISA, IF, FuncS | Human Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS-0125-FY69. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: WB, IF, FuncS
Application: ELISA, Block, WB, FC, IP
Application: ELISA, Cyt, PP, Inhib
Application: ELISA, Activ, Block
-1.png)
Application: WB, ELISA, FuncS
Application: ELISA, FC, FuncS
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
