Human Anti-hla (clone MEDI4893) scFv-Fc Chimera
CAT#: VS-0325-FY151
The Anti-α-Hemolysin scFv-Fc antibody is a promising new tool with potential research, diagnostic, and therapeutic applications. This antibody specifically targets α-hemolysin (α-HL), a key virulence factor of S. aureus, and exhibits high specificity towards this toxin, showing binding to S. aureus but not to S. albicans. The scFv-Fc format, consisting of a single-chain variable fragment fused to the Fc region of human IgG, provides advantages such as increased serum half-life and the potential for effector functions.
Specifications
- Immunogen
- The immunogen was purified α-hemolysin protein.
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- High specificity towards α-HL. The antibody showed specific binding to S. aureus but not to S. albicans.
- Species Reactivity
- S. aureus
- Clone
- MEDI4893
- Applications
- ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- hla, alpha-toxin; Staphylococcus aureus alpha-hemolysin
- Long Name
- Staphylococcus aureus alpha-hemolysin
- Function
- Staphylococcus aureus hla (alpha-hemolysin) is a pore-forming toxin that damages host cell membranes. It contributes to bacterial virulence and is implicated in various staphylococcal infections.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "Clone MEDI4893"
- CAT
- Product Name
See other products for "Hla"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-358CL | Anti-Human Hla Recombinant Antibody (TAB-358CL) | FuncS, Neut | Antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-332 | Recombinant Human Anti-S.Aureus a-hemolysin Antibody | WB, ELISA, IF, FuncS | IgG |
| PABL-396 | Recombinant Human Anti-S. aureus Hla Antibody (MEDI4893) | BL | IgG |
| PABL-696 | Recombinant Human Anti-S. aureus a-hemolysin Antibody | WB, IHC, IF, FuncS | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-332 | Recombinant Human Anti-S.Aureus a-hemolysin Antibody scFv Fragment | WB, ELISA, IF, FuncS | scFv |
| PSBL-395 | Recombinant Human Anti-S. aureus Hla Antibody scFv Fragment (MEDI4893) | BL | scFv |
| PSBL-689 | Recombinant Human Anti-S. aureus a-hemolysin Antibody scFv Fragment | WB, IHC, IF, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-332 | Recombinant Human Anti-S.Aureus a-hemolysin Antibody Fab Fragment | WB, ELISA, IF, FuncS | Fab |
| PFBL-395 | Recombinant Human Anti-S. aureus Hla Antibody Fab Fragment (MEDI4893) | BL | Fab |
| PFBL-689 | Recombinant Human Anti-S. aureus a-hemolysin Antibody Fab Fragment | WB, IHC, IF, FuncS | Fab |
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