Human Anti-hla (clone MEDI4893) scFv-Fc Chimera (CAT#: VS-0325-FY151)
The Anti-α-Hemolysin scFv-Fc antibody is a promising new tool with potential research, diagnostic, and therapeutic applications. This antibody specifically targets α-hemolysin (α-HL), a key virulence factor of S. aureus, and exhibits high specificity towards this toxin, showing binding to S. aureus but not to S. albicans. The scFv-Fc format, consisting of a single-chain variable fragment fused to the Fc region of human IgG, provides advantages such as increased serum half-life and the potential for effector functions.
Specific Inquiry
Specifications
- Immunogen
- The immunogen was purified α-hemolysin protein.
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- High specificity towards α-HL. The antibody showed specific binding to S. aureus but not to S. albicans.
- Species Reactivity
- S. aureus
- Clone
- MEDI4893
- Applications
- ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- hla, alpha-toxin; Staphylococcus aureus alpha-hemolysin
- Long Name
- Staphylococcus aureus alpha-hemolysin
- Function
- Staphylococcus aureus hla (alpha-hemolysin) is a pore-forming toxin that damages host cell membranes. It contributes to bacterial virulence and is implicated in various staphylococcal infections.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Human Antibody Products
IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-358CL | Anti-Human Hla Recombinant Antibody (TAB-358CL) | FuncS, Neut | Antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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