Human Anti-IL22 scFv-Fc Chimera (VS-0425-FY127)
CAT#: VS-0425-FY127
The anti-IL22 scFv-FC is a recombinant antibody fragment that specifically recognizes and binds to interleukin-22 (IL-22), a cytokine linked to inflammatory conditions, with the goal of blocking its signaling pathways to reduce inflammation and tissue damage.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Not detected
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000127318-IL22
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Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human IL22
- Species Reactivity
- Cynomolgus monkey, Human, Rat
- Applications
- ELISA, Flow Cytometry
- Related Disease
- Scleritis and Acute Generalized Exanthematous Pustulosis
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The optimal dilution concentration is determined by the experiment.
Target
- Alternative Names
- Interleukin 22
- Gene ID
- 50616
- UniProt ID
- Q9GZX6
- Long Name
- Interleukin 22
- Sequence Similarities
- Belongs to the IL-10 family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- Glycosylation at Asn54, Asn68, and Asn97
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 3 sites
- Protein Refseq
- NP_065386.1
- Function
- Cytokine that plays a critical role in modulating tissue responses during inflammation.
Plays an essential role in the regeneration of epithelial cells to maintain barrier function after injury and for the prevention of further tissue damage.
Unlike most of the cytokines, has no effect on immune cells.
Signals through a heterodimeric receptor composed of two subunits, the specific receptor IL22RA1 which is present on non-immune cells in many organs and the shared subunit IL10RB.
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Related Diseases
Inflammatory Bowel Diseases
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "IL22"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1442-sdAb | Recombinant Anti-Human IL22 VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-748 | Anti-IL22 Recombinant Antibody (TAB-748) | WB, IP, IF, FuncS, FC, Neut, ELISA | IgG1 - lambda |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-591LC | Anti-human IL22 Recombinant Antibody (266.16.1.4.4.1) (TAB-591LC) | ELISA, FC, IHC | |
| TAB-592LC | Anti-human IL22 Recombinant Antibody (267.17.1.1.4.1) (TAB-592LC) | ELISA, FC, IHC | |
| TAB-591LC-S(P) | Anti-human IL22 scFv Fragment (266.16.1.4.4.1) | ELISA, FC, IHC | |
| TAB-592LC-S(P) | Anti-human IL22 scFv Fragment (267.17.1.1.4.1) | ELISA, FC, IHC | |
| TAB-593LC-S(P) | Anti-human IL22 scFv Fragment (266.5.1.2.2.3) | ELISA, FC, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1328CQ | Mouse Anti-IL22 Recombinant Antibody (clone CBL551) | Neut | Mouse IgG1 |
| NEUT-1329CQ | Mouse Anti-IL22 Recombinant Antibody (clone CBL972) | ELISA, Neut | Mouse IgG1 |
| NEUT-1330CQ | Rat Anti-IL22 Recombinant Antibody (clone VC22) | FuncS, Neut | Rat IgG2a, κ |
| NEUT-1331CQ | Rat Anti-Il22 Recombinant Antibody (VMC197) | Neut | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1803 | Rabbit Anti-IL22 Recombinant Antibody (clone DS1803AB) | WB | Rabbit IgG |
| MOR-4614 | Rabbit Anti-IL22 Recombinant Antibody (clone TH127DS) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0305-YC | Human Anti-IL22 Recombinant Antibody (HPAB-0305-YC) | ELISA, FuncS | Human IgG |
| VS-0723-WK100 | Human Anti-IL22 Recombinant Antibody (VS-0723-WK100) | FC | Chimeric (rabbit/human) IgG1 |
| VS3-WK1728 | Recombinant Rabbit Anti-IL22 Capture Antibody (clone R06-5Q1) | ELISA | Rabbit IgG |
| VS3-WK1729 | Recombinant Rabbit Anti-IL22 Detection Antibody (clone R09-4O1) | ELISA | Rabbit IgG |
| VS7-0425-WR139 | Mouse Anti-IL22 Recombinant Antibody (clone 2A10B9) | IHC, ICC, FC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0305-YC-S(P) | Human Anti-IL22 Recombinant Antibody; scFv Fragment (HPAB-0305-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-0413-CN-S(P) | Human Anti-IL22 Recombinant Antibody; scFv Fragment (HPAB-0413-CN-S(P)) | ELISA, Block | Human scFv |
| HPAB-0414-CN-S(P) | Human Anti-IL22 Recombinant Antibody; scFv Fragment (HPAB-0414-CN-S(P)) | ELISA, Block | Human scFv |
| HPAB-0416-CN-S(P) | Human Anti-IL22 Recombinant Antibody; scFv Fragment (HPAB-0416-CN-S(P)) | ELISA, Block | Human scFv |
| HPAB-0830-WJ-S(P) | Human Anti-IL22 Recombinant Antibody; scFv Fragment (HPAB-0830-WJ-S(P)) | ELISA, WB | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0413-CN-F(E) | Human Anti-IL22 Recombinant Antibody; Fab Fragment (HPAB-0413-CN-F(E)) | ELISA, Block | Human Fab |
| HPAB-0830-WJ-F(E) | Human Anti-IL22 Recombinant Antibody; Fab Fragment (HPAB-0830-WJ-F(E)) | ELISA, WB | Humanized Fab |
| HPAB-0831-WJ-F(E) | Human Anti-IL22 Recombinant Antibody; Fab Fragment (HPAB-0831-WJ-F(E)) | ELISA, WB | Humanized Fab |
| HPAB-0832-WJ-F(E) | Human Anti-IL22 Recombinant Antibody; Fab Fragment (HPAB-0832-WJ-F(E)) | ELISA, WB | Humanized Fab |
| HPAB-0833-WJ-F(E) | Human Anti-IL22 Recombinant Antibody; Fab Fragment (HPAB-0833-WJ-F(E)) | ELISA, WB | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-748 | Afuco™ Anti-IL22 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-748) | IP, IF, FuncS, FC, Neut | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY134 | CytoStream™ Mouse Anti-IL22 Recombinant Antibody (VS-0225-XY134) | FC | Mouse IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3513 | Anti-IL22 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC178 | Recombinant Anti-IL22 Eliminating Antibody, pH-Sensitive (VS-0625-YC178) | Antigen-Sweeping In Vivo. | Human IgG1 lambda |
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