Human Anti-IL9 (clone 71A10) scFv-Fc Chimera
CAT#: VS-0425-FY133
The anti-IL9 scFv-FC is a specialized fusion protein designed to neutralize interleukin-9 (IL-9), a cytokine associated with various allergic and autoimmune diseases. This single-chain variable fragment fused to an Fc portion enhances its stability and prolongs its half-life in circulation, allowing for effective modulation of IL-9-driven pathways, which could lead to innovative treatments for conditions like asthma and eczema.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enriched (HDLM-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000145839-IL9
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Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human IL9
- Species Reactivity
- Human
- Clone
- 71A10
- Applications
- Immunoassay
- Related Disease
- Autoimmune disease, an inflammatory disease
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The optimal dilution concentration is determined by the experiment.
Target
- Alternative Names
- Interleukin 9
- Gene ID
- 3578
- UniProt ID
- P15248
- Long Name
- Interleukin 9
- Sequence Similarities
- Belongs to the IL-7/IL-9 family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- Glycosylation at Asn50, Asn63, Asn78, and Asn114
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 4 sites
- Protein Refseq
- NP_000581.1
- Function
- Affects intestinal epithelial permeability and adaptive immunity
In addition, induces the differentiation of specific T-cell subsets such as IL-17 producing helper T-cells (TH17) and also proliferation and differentiation of mast cells
Mechanistically, exerts its biological effects through a receptor composed of IL9R subunit and a signal transducing subunit IL2RG
Receptor stimulation results in the rapid activation of JAK1 and JAK3 kinase activities leading to STAT1, STAT3 and STAT5-mediated transcriptional programs
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Related Diseases
Asthma
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone 71A10"
- CAT
- Product Name
See other products for "IL9"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1792z | Mouse Anti-IL9 Recombinant Antibody (clone 4H10) | WB, ELISA, IHC | Mouse IgG2b |
| HPAB-1865-FY | Human Anti-IL9 Recombinant Antibody (clone 4D4) | ELISA | Human IgG |
| HPAB-1866-FY | Human Anti-IL9 Recombinant Antibody (clone 7F3) | ELISA | Human IgG |
| HPAB-1867-FY | Human Anti-IL9 Recombinant Antibody (clone 71A10) | ELISA | Human IgG |
| VS-0322-LC99 | Mouse Anti-IL9 Recombinant Antibody (clone mMH9A4) | ELISA, FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-220 | Anti-Human IL9 Recombinant Antibody (TAB-220) | WB, Neut, ELISA, IF, IP, FuncS, FC | IgG1 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1514CQ | Mouse Anti-IL9 Recombinant Antibody (clone CBL656) | Neut | Mouse IgG1 |
| NEUT-1515CQ | Mouse Anti-IL9 Recombinant Antibody (clone MH9A3) | ELISA, Neut | Mouse IgG1, κ |
| NEUT-1516CQ | Mouse Anti-IL9 Recombinant Antibody (clone MH9D1) | ELISA, Neut | Mouse IgG1, κ |
| NEUT-1518CQ | Rat Anti-Il9 Recombinant Antibody (clone CBL588) | Neut | Rat IgG2b |
| NEUT-1519CQ | Hamster Anti-Il9 Recombinant Antibody (clone D9302C12) | Neut, WB | Hamster IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1517CQ | Mouse Anti-Il9 Recombinant Antibody (clone 9C1) | Block | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1818 | Rabbit Anti-IL9 Recombinant Antibody (clone DS1818AB) | WB | Rabbit IgG |
| MOR-4626 | Rabbit Anti-IL9 Recombinant Antibody (clone TH139DS) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-220 | Afuco™ Anti-IL9 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-220) | Neut, ELISA, IF, IP, FuncS | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1759-FY-F(E) | Mouse Anti-IL9 Recombinant Antibody (clone 4D4); scFv Fragment | ELISA | Mouse scFv |
| HPAB-1760-FY-F(E) | Mouse Anti-IL9 Recombinant Antibody (clone 4D4H2-1-D11); scFv Fragment | ELISA | Mouse scFv |
| HPAB-1865-FY-F(E) | Human Anti-IL9 Recombinant Antibody (clone 4D4); scFv Fragment | ELISA | Human scFv |
| HPAB-1866-FY-F(E) | Human Anti-IL9 Recombinant Antibody (clone 7F3); scFv Fragment | ELISA | Human scFv |
| HPAB-1867-FY-F(E) | Human Anti-IL9 Recombinant Antibody (clone 71A10); scFv Fragment | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1759-FY-S(P) | Mouse Anti-IL9 Recombinant Antibody (clone 4D4); Fab Fragment | ELISA | Mouse Fab |
| HPAB-1760-FY-S(P) | Mouse Anti-IL9 Recombinant Antibody (clone 4D4H2-1-D11); Fab Fragment | ELISA | Mouse Fab |
| HPAB-1865-FY-S(P) | Human Anti-IL9 Recombinant Antibody (clone 4D4); Fab Fragment | ELISA | Human Fab |
| HPAB-1866-FY-S(P) | Human Anti-IL9 Recombinant Antibody (clone 7F3); Fab Fragment | ELISA | Human Fab |
| HPAB-1867-FY-S(P) | Human Anti-IL9 Recombinant Antibody (clone 71A10); Fab Fragment | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY147 | CytoStream™ Armenian Hamster Anti-IL9 Recombinant Antibody (clone D9302C12) | FC | Armenian Hamster IgG2, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC193 | Recombinant Anti-IL9 Eliminating Antibody, pH-Sensitive (VS-0625-YC193) | Antigen-Sweeping In Vivo. | Mouse IgG1 kappa |
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