Recombinant Human Anti-KCNQ1 Soluble TCR (MA3) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF745)
Human TCR (MA3) recognizes KCNQ1 peptide (FLPDLNANA) in the context of HLA-A*02:01. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (MA3). Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line THP-1
(Immunofluorescent staining of human cell line THP-1 shows localization to plasma membrane & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/71107/2061_D8_1_selected.jpg
(Immunofluorescent staining of human cell line THP-1 shows localization to plasma membrane & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/71107/2061_D8_1_selected.jpg
Figure 2 Adrenal gland
(High expression in adrenal gland)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_B_4_5_val_selected.jpg
(High expression in adrenal gland)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_B_4_5_val_selected.jpg
Figure 3 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_A_7_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_A_7_5.jpg
Figure 4 Thyroid gland
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_B_3_5.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_B_3_5.jpg
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_A_7_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_A_7_4.jpg
Figure 6 RNA cell line category: Cell line enhanced (HMC-1, OE19, RPMI-8226, U-266/70, U-937)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000053918-KCNQ1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000053918-KCNQ1
Specifications
- Host Species
- Human
- Target
- KCNQ1
- Species Reactivity
- Human
- Epitope
- FLPDLNANA
- MHC
- HLA-A*02:01
- Clone
- MA3
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- Related Disease
- Others
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- LQT; RWS; WRS; LQT1; SQT2; ATFB1; ATFB3; JLNS1; KCNA8; KCNA9; Kv1.9; Kv7.1; KVLQT1
- Gene ID
- 3784
- UniProt ID
- P48547
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0381MZ | Recombinant Mouse Anti-Human KCNQ1 Antibody (clone T38A-11) | ELISA | Mouse antibody |
| VS3-QX633 | Mouse Anti-KCNQ1 Recombinant Antibody (clone 7E1-F6-F10) | WB, IHC, ICC, FC, ELISA | Mouse IgG2b |
| VS7-0425-WR187 | Mouse Anti-KCNQ1 Monoclonal Antibody (clone 5E12) | WB, FC | Mouse IgG2b |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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