Recombinant Human Anti-KCNQ1 Soluble TCR (MA3) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF745)
Human TCR (MA3) recognizes KCNQ1 peptide (FLPDLNANA) in the context of HLA-A*02:01. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (MA3). Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line THP-1
(Immunofluorescent staining of human cell line THP-1 shows localization to plasma membrane & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/71107/2061_D8_1_selected.jpg
(Immunofluorescent staining of human cell line THP-1 shows localization to plasma membrane & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/71107/2061_D8_1_selected.jpg
Figure 2 Adrenal gland
(High expression in adrenal gland)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_B_4_5_val_selected.jpg
(High expression in adrenal gland)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_B_4_5_val_selected.jpg
Figure 3 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_A_7_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_A_7_5.jpg
Figure 4 Thyroid gland
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_B_3_5.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_B_3_5.jpg
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_A_7_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_A_7_4.jpg
Figure 6 RNA cell line category: Cell line enhanced (HMC-1, OE19, RPMI-8226, U-266/70, U-937)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000053918-KCNQ1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000053918-KCNQ1
Specifications
- Host Species
- Human
- Target
- KCNQ1
- Species Reactivity
- Human
- Epitope
- FLPDLNANA
- MHC
- HLA-A*02:01
- Clone
- MA3
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- Related Disease
- Others
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- LQT; RWS; WRS; LQT1; SQT2; ATFB1; ATFB3; JLNS1; KCNA8; KCNA9; Kv1.9; Kv7.1; KVLQT1
- Gene ID
- 3784
- UniProt ID
- P48547
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0381MZ | Recombinant Mouse Anti-Human KCNQ1 Antibody (clone T38A-11) | ELISA | Mouse antibody |
| VS3-QX633 | Mouse Anti-KCNQ1 Recombinant Antibody (clone 7E1-F6-F10) | WB, IHC, ICC, FC, ELISA | Mouse IgG2b |
| VS7-0425-WR187 | Mouse Anti-KCNQ1 Monoclonal Antibody (clone 5E12) | WB, FC | Mouse IgG2b |
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