Human Anti-KMA (clone cK121) scFv-Fc Chimera (CAT#: VS-0425-FY140)
The anti-KMA scFv-FC is a single-chain variable fragment fused to the Fc region of an immunoglobulin, designed to target the KMA (Keratins and Myeloma Antigens) marker. This product enhances the specificity and binding affinity to KMA-expressing cells, making it a valuable tool for the detection and potential therapeutic targeting of myeloma cells. Its unique design allows for improved stability and solubility, facilitating various applications in research and clinical settings, including immunotherapy and diagnostics.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Immunogen
- K121 recognizes free kappa light chains and an antigen on kappa-type myeloma cells.
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human KMA
- Species Reactivity
- Human
- Clone
- cK121
- Applications
- ELISA, Flow Cytometry
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- In cytotoxicity assays, murine K121 was used at 5.5 μM, and chimaeric K121 (cK121) at 0.8 μM.
The optimal dilution concentration is determined by the experiment.
Target
- Alternative Names
- KMA; kappa myeloma antigen
- Long Name
- kappa myeloma antigen
- Function
- Myeloma antigens play key roles in the biology of multiple myeloma and are critical targets for the development of effective treatments.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone cK121"
See other products for "KMA"
Select a product category from the dropdown menu below to view related products.
Please select product type
Immunotoxin Products
Rat Antibody Products
Chimeric Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L030M | anti-KMA immunotoxin K121 (scFv)-Mel | Cytotoxicity assay, Functional assay |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS-0425-FY140. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: FC, IHC, FuncS, Inhib, Cyt
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, WB
Application: WB, ELISA, IF
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, IHC, IF, IP, FC, FuncS
Application: ELISA, IF, Block, FuncS
Application: ELISA, WB
Application: ELISA, WB, IF, FC, IP
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
