Recombinant Human Anti-NY-ESO-1 Soluble TCR (TE8-1-8F) (KIH) (CAT#: VS-0622-YF5472)
Human TCR (TE8-1-8F) recognizes NY-ESO-1 peptide (SLLMWTTQV) in the context of HLA-A2. Soluble TCR is expressed with Knob-in-hole (KIH) strategy (scTCR-hIgG Knob, scTCR-hIgG Hole). Please note that the activity is not guaranteed.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in testis.
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13061/ihc_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13061/ihc_selected.jpg
Figure 2 Low expression in endometrium 1.
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13061/32112_B_4_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13061/32112_B_4_3_val_selected.jpg
Figure 3 Testis
(Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13061/32112_A_6_6.jpg
(Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13061/32112_A_6_6.jpg
Figure 4 RNA cell line category: Group enriched (U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000268651-CTAG1A
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000268651-CTAG1A
Specifications
- Host Species
- Human
- Target
- NY-ESO-1
- Species Reactivity
- Human
- Epitope
- SLLMWTTQV
- MHC
- HLA-A2
- Clone
- TE8-1-8F
- Type
- Soluble TCR (KIH)
- Related Disease
- Melanoma
- TCR Expression Strategy
- KIH strategy: scTCR-human IgG Knob and scTCR-human IgG Hole can form heterodimer based on Knob-in-hole (KIH) strategy. The soluble TCR contains single chain TCR. With this KIH antibody production strategy, VL/VH will be replaced with Valpha-linker-Vbeta (single chain TCR).
Target
- Alternative Names
- CTAG1A; CT6.1; CTAG; Cancer/Testis Antigen 6.1; Cancer/Testis Antigen 1; Autoimmunogenic Cancer/Testis Antigen NY-ESO-1; CTAG1; LAGE2A
- Gene ID
- 246100
- UniProt ID
- P78358
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IgG Antibody Products
MHC Tetramer Products for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3805z | Mouse Anti-CTAG1A Recombinant Antibody (clone 35B7) | WB, IP, IF, IHC | Mouse IgG1, κ |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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