Recombinant Human Anti-NY-ESO-1 Soluble TCR (ZIP-Fos/ZIP-Jun) (VS-0622-YF55)
CAT#: VS-0622-YF55
Human TCR recognizes NY-ESO-1 peptide (AMPFATPM) in the context of HLA-B*3508. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR. Please note that the activity is not guaranteed.
Gene Expression
Normal Tissue
Figure 1 High expression in testis.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13061/ihc_selected.jpg
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Specifications
- Host Species
- Human
- Target
- NY-ESO-1
- Species Reactivity
- Human
- Epitope
- AMPFATPM
- MHC
- HLA-B*3508
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- Related Disease
- Melanoma, breast cancer, lung cancer, prostate cancer, thyroid cancer, ovarian cancer, or synovial cell sarcoma.
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
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