Human Anti-PSMA scFv-Fc Chimera (VS-0125-FY102)
CAT#: VS-0125-FY102
Anti-PSMA scFv-Fc antibodies are engineered single-chain antibodies that contain an Fc fragment, enabling them to easily bind to Fc receptors. This interaction activates the immune system's complement system, contributing to their anti-tumor effects. These antibodies show great potential for applications in cancer imaging and therapy, effectively targeting Prostate-Specific Membrane Antigen (PSMA), thereby improving the accuracy and efficacy of treatments. Furthermore, these scFv-Fc antibodies have demonstrated excellent targeting capabilities in preclinical and clinical studies, offering new opportunities for personalized treatment of cancer patients.
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Species Reactivity
- Human
- Applications
- Bioimaging
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Stabilizer
- No Stabilizers
- Sterility
- 0.2 μM filtered
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The main function of scFv-Fc is to specifically bind to target antigens in vivo, which can be used for imaging (such as immuno-PET) or therapy (such as antibody-mediated therapies). Its construction combines the high affinity of scFv with the long half-life of the Fc region, enhancing serum half-life and providing immune system-mediated effects.
Target
- Alternative Names
- Folate Hydrolase 1 (FOLH1), Glutamate Carboxypeptidase II (GCPII), NAALADase, N-acetylated alpha-linked acidic dipeptidase
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "PSMA"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1030LY-S(P) | Human Anti-PSMA Recombinant Antibody; scFv Fragment (HPAB-1030LY-S(P)) | ELISA | Human scfv |
HPAB-1031LY-S(P) | Human Anti-PSMA Recombinant Antibody; scFv Fragment (HPAB-1031LY-S(P)) | ELISA | Human scfv |
HPAB-1032LY-S(P) | Human Anti-PSMA Recombinant Antibody; scFv Fragment (HPAB-1032LY-S(P)) | ELISA | Human scfv |
HPAB-1033LY-S(P) | Human Anti-PSMA Recombinant Antibody; scFv Fragment (HPAB-1033LY-S(P)) | ELISA | Human scfv |
HPAB-1034LY-S(P) | Human Anti-PSMA Recombinant Antibody; scFv Fragment (HPAB-1034LY-S(P)) | ELISA | Human scfv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1029LY | Human Anti-PSMA Recombinant Antibody (HPAB-1029LY) | ELISA | Human IgG |
HPAB-1030LY | Human Anti-PSMA Recombinant Antibody (HPAB-1030LY) | ELISA | Human IgG |
HPAB-1031LY | Human Anti-PSMA Recombinant Antibody (HPAB-1031LY) | ELISA | Human IgG |
HPAB-1032LY | Human Anti-PSMA Recombinant Antibody (HPAB-1032LY) | ELISA | Human IgG |
HPAB-1033LY | Human Anti-PSMA Recombinant Antibody (HPAB-1033LY) | ELISA | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1029LY-F(E) | Human Anti-PSMA Recombinant Antibody; Fab Fragment (HPAB-1029LY-F(E)) | ELISA | Human Fab |
HPAB-1030LY-F(E) | Human Anti-PSMA Recombinant Antibody; Fab Fragment (HPAB-1030LY-F(E)) | ELISA | Human Fab |
HPAB-1031LY-F(E) | Human Anti-PSMA Recombinant Antibody; Fab Fragment (HPAB-1031LY-F(E)) | ELISA | Human Fab |
HPAB-1032LY-F(E) | Human Anti-PSMA Recombinant Antibody; Fab Fragment (HPAB-1032LY-F(E)) | ELISA | Human Fab |
HPAB-1033LY-F(E) | Human Anti-PSMA Recombinant Antibody; Fab Fragment (HPAB-1033LY-F(E)) | ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0325-XY1774 | Anti-PSMA Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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