Human Anti-SEB (clone SEB3-2-7) scFv-Fc Chimera (CAT#: VS-0325-FY90)

An anti-SEB scFv-Fc antibody is a recombinant antibody that binds to SEB and combines the antigen-binding capabilities of an scFv with the Fc region of an immunoglobulin. The Fc region provides increased stability and effector functions.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
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  • Isotype Switching:
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  • Datasheet
  • MSDS
  • COA

Specifications

  • Host Species
  • Human
  • Type
  • Human IgG1, scFv-Fc
  • Specificity
  • S. aureus SEB
  • Species Reactivity
  • S. aureus
  • Clone
  • SEB3-2-7
  • Applications
  • ELISA
  • Related Disease
  • Cancer

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Target

  • Alternative Names
  • Enterotoxin type B, Seb
  • Long Name
  • Staphylococcal enterotoxin B
  • Sequence Similarities
  • Belongs to the staphylococcal/streptococcal toxin family.
  • Cellular Localization
  • Secreted
  • Function
  • Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of pro-inflammatory cytokines (PubMed:2303780, PubMed:25015819).
    Causes also the intoxication staphylococcal food poisoning syndrome (By similarity).

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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