Human Anti-TPBG (clone ASN004) scFv-Fc Chimera
CAT#: VS-0125-FY114
The antibody is a single-chain variable fragment (ScFv) derived from human immunoglobulin G1 (huIgG1), with an estimated molecular weight of 106.7 kDa. The 5T4 gene encodes a leucine-rich glycoprotein that spans the membrane and is likely involved in cell adhesion processes. This protein acts as an oncofetal antigen, displaying specificity for trophoblast cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10554/if_selected.jpg
Normal Tissue
Figure 2 Seminal vesicle
High expression in seminal vesicle
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10554/26240_A_7_6_val_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10554/26240_B_7_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10554/26240_A_7_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10554/26240_A_9_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10554/26240_A_8_5.jpg
Normal Tissue
Figure 7 Placenta
Decidual cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Trophoblastic cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10554/26240_A_2_7.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced.
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000146242-TPBG
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Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Species Reactivity
- Human
- Clone
- ASN004
- Applications
- ELISA, Flow Cytometry, Functional Assay
- MW
- It has a predicted MW of 106.7 kDa.
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Format
- Lyophilized
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- Lyophilized from 25 mM histidine, pH6.2, 8% sucrose, 0.01% Tween80
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
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- Product Name
Isotype Control
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- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-118-F(E) | Anti-Human 5T4 Recombinant Antibody Fab Fragment, 5T4 (TAB-118-F(E)) | FuncS, IF, Neut, ELISA, FC, IP, ICC | Fab - G1 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3649 | Rabbit Anti-TPBG Recombinant Antibody (clone DS3649AB) | WB, ICC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0088CQ | Human Anti-TPBG Recombinant Antibody (HPAB-0088CQ) | ELISA, FC, FuncS | Human IgG1, κ |
| HPAB-0089CQ | Human Anti-TPBG Recombinant Antibody (HPAB-0089CQ) | ELISA, FC, FuncS | Human IgG1, κ |
| HPAB-0090CQ | Human Anti-TPBG Recombinant Antibody (HPAB-0090CQ) | ELISA, FC, FuncS | Human IgG1, κ |
| HPAB-0091CQ | Mouse Anti-TPBG Recombinant Antibody (HPAB-0091CQ) | ELISA, FC, FuncS | Mouse IgG, κ |
| HPAB-0092CQ | Mouse Anti-TPBG Recombinant Antibody (HPAB-0092CQ) | ELISA, FC | Mouse IgG, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0088CQ-S(P) | Human Anti-TPBG Recombinant Antibody; scFv Fragment (HPAB-0088CQ-S(P)) | ELISA, FC | Human scFv |
| HPAB-0089CQ-S(P) | Human Anti-TPBG Recombinant Antibody; scFv Fragment (HPAB-0089CQ-S(P)) | ELISA, FC | Human scFv |
| HPAB-0090CQ-S(P) | Human Anti-TPBG Recombinant Antibody; scFv Fragment (HPAB-0090CQ-S(P)) | ELISA, FC | Human scFv |
| HPAB-0091CQ-S(P) | Mouse Anti-TPBG Recombinant Antibody; scFv Fragment (HPAB-0091CQ-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0092CQ-S(P) | Mouse Anti-TPBG Recombinant Antibody; scFv Fragment (HPAB-0092CQ-S(P)) | ELISA, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0088CQ-F(E) | Human Anti-TPBG Recombinant Antibody; Fab Fragment (HPAB-0088CQ-F(E)) | ELISA, FC | Human Fab |
| HPAB-0089CQ-F(E) | Human Anti-TPBG Recombinant Antibody; Fab Fragment (HPAB-0089CQ-F(E)) | ELISA, FC | Human Fab |
| HPAB-0090CQ-F(E) | Human Anti-TPBG Recombinant Antibody; Fab Fragment (HPAB-0090CQ-F(E)) | ELISA, FC | Human Fab |
| HPAB-0091CQ-F(E) | Mouse Anti-TPBG Recombinant Antibody; Fab Fragment (HPAB-0091CQ-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0645-WJ-F(E) | Human Anti-TPBG Recombinant Antibody; Fab Fragment (HPAB-0645-WJ-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN1281 | PE-H-2Db/Human TPBG (ASFRNLTHL) MHC Tetramer | FCM, IHC | |
| MHC-CN1282 | APC-H-2Db/Human TPBG (ASFRNLTHL) MHC Tetramer | FCM, IHC | |
| MHC-CN1283 | FITC-H-2Db/Human TPBG (ASFRNLTHL) MHC Tetramer | FCM, IHC | |
| MHC-CN1284 | H-2Db/Human TPBG (ASFRNLTHL) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY60 | Human Anti-TPBG (clone H8) scFv-Fc Chimera | FC, ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC638 | Recombinant Anti-TPBG Vesicular Antibody, EV Displayed (VS-0425-YC638) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7454 | Anti-TPBG Immunohistochemistry Kit | IHC | |
| VS-0525-XY7455 | Anti-Mouse TPBG Immunohistochemistry Kit | IHC |
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