Human Anti-TRBC1 (clone IARC307) scFv-Fc Chimera (CAT#: VS-0325-FY5)

• Host Species
• Human

• Type
• Human IgG1, scFv-Fc

• Specificity
• Human TRBC1

• Species Reactivity
• Human

• Clone
• IARC307

• Applications
• ELISA, Flow Cytometry, Immunofluorescence

• Related Disease
• T-cell lymphoma or leukaemia

• Purity
• >95% as determined by SDS-PAGE

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Ice packs

• Alternative Names
• T Cell Receptor Beta Constant 1; V_segment Translation Product; BV05S1J2.2; TCRBC1; TCRB

• Gene ID
• 28639

• UniProt ID
• P01850

• Long Name
• T Cell Receptor Beta Constant 1

• Cellular Localization
• Cell membrane

• Post Translation Modifications
• Glycosylation at Asn69
  Modification sites at PhosphoSitePlus
  Glycosylation from GlyGen 1 site

• Function
• Constant region of T cell receptor (TR) beta chain (PubMed:24600447).
  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.
  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).
  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.

Isotype Control

• MOB-200CQ
• Human IgG Fc Isotype Control Antibody

Secondary Antibody

• 2ND-029CQ
• Goat Anti-Human IgG Fc Antibody

• FAMAB-1510CQ
• Human Anti-TRBC1 Recombinant Antibody (clone IARC307)

• FAMAB-1510CQ-mRNA
• Human Anti-TRBC1 Antibody (clone IARC307), mRNA

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