Recombinant Human Anti-Tyrosinase Soluble TCR (B12) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF459)
Human TCR (B12) recognizes Tyrosinase peptide (YMDGTMSQV) in the context of HLA-A*0201. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (B12). Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location and Protein Expression
RNA Expression
Figure 1 IF staining of human cell line SK-MEL-30
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43241/1291_D5_4_selected.jpg
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43241/1291_D5_4_selected.jpg
Figure 2 RNA cell line category: Cell line enriched (SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000077498-TYR/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000077498-TYR/subcellular
Specifications
- Host Species
- Human
- Target
- Tyrosinase
- Species Reactivity
- Human
- Epitope
- YMDGTMSQV
- MHC
- HLA-A*0201
- Clone
- B12
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- Related Disease
- Melanomas, gliomas , glioblastoma
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
Related Resources
Cocaine Addiction
Amphetamine Addiction
Alcoholism
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone B12"
See other products for "Tyr"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1019 | Recombinant Anti-Tyr Antibody | ELISA, WB, IP, FuncS | IgG |
| MHH-1019 | Recombinant Human Anti-Tyr Antibody | RIA, IF, FuncS | IgG |
| MRO-1543-CN | Mouse Anti-TYR Recombinant Antibody (clone C2-B5) | WB, IF, IHC, FC | Mouse IgG1 |
| MRO-1544-CN | Rabbit Anti-TYR Recombinant Antibody (clone JA52-11) | WB, IF, IHC | Rabbit IgG |
| MRO-2248-CN | Rabbit Anti-TYR Polyclonal Antibody (MRO-2248-CN) | WB, IF, IHC, FC | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1019-F(E) | Recombinant Anti-Tyr Antibody Fab Fragment | RIA, WB, FuncS | Fab |
| MHH-1019-F(E) | Recombinant Human Anti-Tyr Antibody Fab Fragment | ELISA, WB, FC, FuncS | Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1019-S(P) | Recombinant Anti-Tyr Antibody scFv Fragment | ELISA, IF, FuncS | scFv |
| MHH-1019-S(P) | Recombinant Human Anti-Tyr Antibody scFv Fragment | WB, Neut, FuncS | scFv |
MHC Tetramer for Cancer
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3734 | Rabbit Anti-TYR Recombinant Antibody (clone DS3734AB) | IHC-P, WB, ICC, IF | Rabbit IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS-0622-YF459. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.