Recombinant Human Anti-Tyrosinase Soluble TCR (C-Cys) (VS-0622-YF3170)
CAT#: VS-0622-YF3170
Human TCR recognizes Tyrosinase peptide (YMDGTMSQV) in the context of HLA-A*0201. Soluble TCR is expressed with C-terminal Cys strategy (TRAV-TRAC partial-Cys, TRBV-TRBC partial-Cys). Depending the C-terminal Cys, two chains form heterodimer. Please note that the activity is not guaranteed.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line SK-MEL-30
Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43241/1291_D5_4_selected.jpg
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Specifications
- Host Species
- Human
- Target
- Tyrosinase
- Species Reactivity
- Human
- Epitope
- YMDGTMSQV
- MHC
- HLA-A*0201
- Type
- Soluble TCR (C-Cys)
- Related Disease
- Melanomas, gliomas , glioblastoma
- TCR Expression Strategy
- C-Cys strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on C-terminal Cys. The soluble TCR contains variable regions and partial constant regions.
Target
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Related Diseases
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Alcoholism
Downloadable Resources
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Datasheet
MSDS
COA
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