Human Anti-VEEV (clone 3B4C-4) scFv-Fc Chimera
CAT#: VS-0125-FY106
The scFv-Fc fusion protein that targets VEEV has shown promising progress in combating Venezuelan equine encephalitis virus (VEEV). It combines specificity, stability, and enhanced immune interactions, effectively targeting this dangerous virus. The scFv-Fc fusion protein has multiple functions. First, it can specifically recognize and bind to particular antigens, such as VEEV. Second, the introduction of the Fc region significantly enhances the stability and binding capability of this molecule, resulting in better performance compared to pure scFv. Additionally, the Fc region can interact with receptors on other immune cells, thereby further enhancing the immune response through antibody-dependent cellular cytotoxicity (ADCC) or complement-mediated lysis.
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Species Reactivity
- Venezuelan equine encephalitis virus (VEEV)
- Clone
- 3B4C-4
- Applications
- Antibody-dependent cellular cytotoxicity
- Related Disease
- Venezuelan equine encephalitis virus (VEEV) infection
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Stabilizer
- No Stabilizers
- Sterility
- 0.2 μM filtered
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- scFv-Fc fusion proteins specifically bind to antigens such as VEEV, enhancing molecular stability and activity. Additionally, the Fc region can induce downstream immune responses, augmenting antibody-dependent cellular cytotoxicity (ADCC) or complement-mediated cytolysis.
Target
- Alternative Names
- Venezuelan Equine Encephalitis Virus, VEEV
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "VEEV"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1035-S(P) | Recombinant Anti-VEEV Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
| MHH-1035-S(P) | Recombinant Human Anti-VEEV Antibody scFv Fragment | ELISA, IF, FuncS | scFv |
| FAMAB-0290-YC-S(P) | Recombinant Mouse Anti-VEEV Antibody scFv Fragment (ch3B4C-4) | ELISA, WB, Neut, FuncS | Mouse scFv |
| HPAB-0767-WJ-S(P) | Recombinant Mouse Anti-VEEV Antibody scFv Fragment (1A3B7) | FC | Mouse scFv |
| HPAB-0768-WJ-S(P) | Recombinant Human Anti-VEEV Antibody scFv Fragment (h1A3B7) | FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-1035 | Recombinant Human Anti-VEEV Antibody | FC, WB, FuncS | IgG |
| FAMAB-0290YC | Recombinant Chimeric (Human/Mouse) Anti-VEEV Antibody (ch3B4C-4) | ELISA, WB, Neut, FuncS | Chimeric (Human/Mouse) IgG1, κ |
| FAMAB-0292YC | Recombinant Chimeric (Human/Mouse) Anti-VEEV Antibody (chHy4-26C) | ELISA, WB, Neut, FuncS | Chimeric (Human/Mouse) IgG1, κ |
| HPAB-0767-WJ | Recombinant Mouse Anti-VEEV Antibody (1A3B7) | WB | Mouse IgG2a |
| HPAB-0768-WJ | Recombinant Human Anti-VEEV Antibody (h1A3B7) | FC | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-1035-F(E) | Recombinant Human Anti-VEEV Antibody Fab Fragment | FC, ELISA, FuncS | Fab |
| FAMAB-0290-YC-F(E) | Recombinant Human Anti-VEEV Antibody Fab Fragment (ch3B4C-4) | ELISA, WB, Neut, FuncS | Human Fab |
| FAMAB-0292-YC-F(E) | Recombinant Human Anti-VEEV Antibody Fab Fragment (chHy4-26C) | ELISA, WB, Neut, FuncS | Human Fab |
| HPAB-0767-WJ-F(E) | Recombinant Mouse Anti-VEEV Antibody Fab Fragment (1A3B7) | FC | Mouse Fab |
| HPAB-0768-WJ-F(E) | Recombinant Human Anti-VEEV Antibody Fab Fragment (h1A3B7) | FC | Human Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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