Humanized Antibody

Antibodies have been the fastest growing class of therapeutic agents in recent years. An obvious efficacy has been achieved on clinic in the treatment of a wide variety of diseases, including cancers and immune disorders, by using antibody-based biotherapeutic agents. Creative Biolabs is one of the first-in class global manufacturers of antibody-based therapeutic agents. In our company, the most cost-effective therapeutic antibody products are available for a variety of in vitro and in vivo studies.

As human anti-mouse antibody (HAMA) response caused by murine antibodies in humans, the usage of this kind of antibodies has been limited. With the development of antibody engineering techniques, it became possible to decrease even further the murine part of antibodies by replacing the hypervariable loops of a fully human antibody with the hypervariable loops of the murine antibody of interest, using an approach called complementarity-determining region (CDR) grafting. These antibodies, called ‘humanized antibodies’, are 85-90% human and are even less immunogenic than chimeric antibodies.

In Creative Biolabs, we guarantee providing you the most comprehensive therapeutic humanized antibody products with high-affinity and high specificity to meet your demands. Meanwhile, if none of the pre-made antibody meets your requirement, you are welcome to contact us, and we will be more than happy to create a custom product for you.

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