Keap1-Nrf2-ARE Pathway Antibody Panel (HMOX1, KEAP1, NFE2L2, NQO1)
CAT#: VS-0725-YC36
The Keap1-Nrf2-ARE Pathway Antibody Panel are sets of 4 antibodies, enabling the simultaneous detection of key proteins involved in this vital regulatory axis. Our comprehensive set includes antibodies against HMOX1, KEAP1, NFE2L2, and NQO1. This panel streamlines your research into oxidative stress, inflammation, and disease pathogenesis, consistently delivering robust and reproducible results for your mechanistic investigations.
| Sub Cat | Component Name | Clone | Type | Target | Species Reactivity | Applications | |
| VS3-XY966 | Mouse Anti-KEAP1 Recombinant Antibody (clone 1F10B6) | 1F10B6 | Mouse IgG1 | KEAP1 | Human | Enzyme-linked Immunosorbent Assay, Western Blot, Flow Cytometry, Immunocytochemistry | |
| VS4-CJ53 | Recombinant Mouse Anti-NFE2L2 Antibody (clone 2F6C6) | 2F6C6 | Mouse IgG2b | NFE2L2 | Human, Mouse | ELISA, WB, IHC, IF, FC | |
| VS3-FY687 | Recombinant Rabbit Anti-HMOX1 Antibody (clone R02-6C1) | R02-6C1 | Rabbit IgG | HMOX1 | Human, Mouse, Rat | Western Blot, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunocytochemistry, Immunofluorescence, Immunoprecipitation | |
| VS3-QX834 | Mouse Anti-NQO1 Recombinant Antibody (clone 4E2-G5-F7) | 4E2-G5-F7 | Mouse IgG1 | NQO1 | Human | WB, IHC, ICC, FC, ELISA |
More Infomation
Specifications
- Targets
- HMOX1, KEAP1, NFE2L2, NQO1
- Species Reactivity
- Human
- Research Area
- Keap1-Nrf2-ARE Pathway
- Introduction
- The Keap1-Nrf2-ARE pathway is arguably the most crucial cellular defense mechanism against oxidative stress, electrophilic insults, and inflammation. It functions as a master regulator, orchestrating the inducible expression of a vast network of genes encoding antioxidant enzymes, detoxification proteins, and other cytoprotective factors. Understanding this pathway is vital for appreciating cellular resilience and for developing therapeutic strategies for a wide range of diseases.
- Storage
- Store at 4°C for up to a week. For long-term storage, store at -20°C or below.
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