MAPK Pathway Antibody Panel (MAPK1, MAPK2, MAPK8, MAPK9, MAPK10, MAPK14)
CAT#: VS-0725-YC1
The MAPK Pathway Antibody Panel are sets of 6 antibodies designed for the simultaneous detection of critical MAPK pathway proteins, including Total MAPK Proteins: MAPK1 (ERK2), MAPK3 (ERK1), MAPK8 (JNK1), MAPK9 (JNK2), MAPK10 (JNK3), and MAPK14 (p38 alpha), alongside Phospho-Specific Targets: MAPK1 (pThr185 / pTyr187), MAPK3 (pThr202 / pTyr204), MAPK8 (pThr183 / pTyr185), MAPK9 (pThr183 / pTyr185), MAPK10 (pThr221 / pTyr223), and MAPK14 (pThr180 / pTyr182). This panel provides a powerful tool for researchers investigating cellular proliferation, differentiation, stress responses, and apoptosis.
| Sub Cat | Component Name | Clone | Type | Target | Species Reactivity | Applications | |
| VS3-QX737 | Mouse Anti-MAPK14 Recombinant Antibody (clone 6E9-E7-F4) | 6E9-E7-F4 | Mouse IgG1 | MAPK14 | Human, Mouse, Monkey, Rat | WB, IHC, ICC, FC, ELISA | |
| VS-0725-YC58 | Rabbit Anti-MAPK8 / MAPK9 / MAPK10 Polyclonal Antibody | Rabbit IgG | MAPK8 / MAPK9 / MAPK10 | Human, Mouse, Rat | IHC, WB | ||
| VS-0725-YC59 | Rabbit Anti-MAPK8 / MAPK9 / MAPK10 (pThr 183 (221) / pTyr185 (223)) Polyclonal Antibody | Rabbit IgG | MAPK8 / MAPK9 / MAPK10 (pThr 183 (221) / pTyr185 (223)) | Human, Mouse, Rat | ICC, IF, WB | ||
| VS-0725-YC60 | Rabbit Anti-MAPK1 / MAPK2 Polyclonal Antibody | Rabbit IgG | MAPK1 / MAPK2 | Human, Mouse, Rat | ICC, IF, IHC, WB | ||
| VS-0725-YC61 | Rabbit Anti-MAPK1 (pThr185 / pTyr187) / MAPK3 (pThr 202 / pTyr 204) Polyclonal Antibody | Rabbit IgG | MAPK1 (pThr185 / pTyr187) / MAPK3 (pThr 202 / pTyr 204) | Human, Mouse, Rat, Dog | ICC, IF, IHC, WB | ||
| VS-0725-YC63 | Rabbit Anti-MAPK14 (pThr 180 / pTyr 182) Polyclonal Antibody | Rabbit IgG | MAPK14 (pThr 180 / pTyr 182) | Human, Mouse, Rat | WB |
More Infomation
Specifications
- Targets
- MAPK1, MAPK3, MAPK1 (pThr185 / pTyr187), MAPK3 (pThr202 / pTyr204), MAPK8, MAPK9, MAPK10, MAPK8 (pThr183 / pTyr185), MAPK9 (pThr183 / pTyr185), MAPK10 (pThr221 / pTyr223), MAPK14, MAPK14 (pThr 180 / pTyr 182)
- Species Reactivity
- Human, Mouse, Rat
- Research Area
- MAPK signaling pathway
- Introduction
- The Mitogen-Activated Protein Kinase (MAPK) signaling pathway represents a fundamental and highly conserved system in eukaryotic cells, orchestrating a vast array of cellular processes from proliferation and differentiation to stress responses, apoptosis, and inflammation. Often described as a three-tiered kinase cascade, it involves sequential phosphorylation events: a MAPK kinase kinase (MAPKKK or MEKK) phosphorylates and activates a MAPK kinase (MAPKK or MKK), which then phosphorylates and activates a MAPK. This phosphorylation typically occurs on specific threonine and tyrosine residues within the MAPK's activation loop.
- Storage
- Store at 4°C for up to a week. For long-term storage, store at -20°C or below.
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