MAPT Phosphorylation Antibody Panel (Total, pSer 396, pSer 404)

CAT#: VS-0725-YC47

The MAPT Phosphorylation Antibody Panel are sets of 6 antibodies, precisely engineered for the simultaneous detection of total MAPT and its critical phosphorylation sites. Our extensive set includes antibodies against total MAPT, and phosphorylated MAPT at pTyr 18, pThr 231, pSer 396, pSer 404, and pSer 422. This panel provides a powerful and streamlined tool for investigating neurodegenerative diseases like Alzheimer's, ensuring robust and reproducible results for your neuropathology studies.

Sub Cat Component Name Clone Type Target Species Reactivity Applications  
HPAB-0498-YJ Mouse Anti-Trans pT231-MAPT Recombinant Antibody (HPAB-0498-YJ) Mouse IgG1 Trans pT231-MAPT Human ELISA, IHC, Neut, FuncS
HPAB-0300-YJ Human Anti-MAPT (pS422) Recombinant Antibody (HPAB-0300-YJ) Humanized IgG1, κ MAPT (pS422) Human FC, ELISA, IF
VS-0224-FY6 Mouse Anti-MAPT (pTyr18) Recombinant Antibody (clone 9G3) 9G3 Mouse IgG2a MAPT Human, Mouse Western Blot, Immunohistochemistry, Immunofluorescence
VS-0725-YC240 Rabbit Anti-MAPT (pSer 404) Polyclonal Antibody Rabbit IgG MAPT (pSer 404) Human, Mouse, Rat ICC, IF, IHC, WB
VS-0725-YC241 Rabbit Anti-MAPT (pSer 396) Polyclonal Antibody Rabbit IgG MAPT (pSer 396) Human, Mouse, Rat IHC, WB
More Infomation

Specifications

  • Targets
  • MAPT (Total, pTyr 18, pThr 231, pSer 396, pSer 404, pSer 422)
  • Species Reactivity
  • Human
  • Research Area
  • MAPT Phosphorylation
  • Introduction
  • MAPT, the gene encoding the Tau protein, is a microtubule-associated protein (MAP) primarily expressed in neurons of the central nervous system. Its main physiological function is to promote the assembly and stability of microtubules, which are crucial components of the neuronal cytoskeleton. Microtubules are essential for maintaining neuronal structure, facilitating axonal transport of organelles and vesicles, and supporting synaptic function. The proper functioning of Tau is intricately regulated by various post-translational modifications, with phosphorylation being the most critical.
  • Storage
  • Store at 4°C for up to a week. For long-term storage, store at -20°C or below.
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