Mouse Anti-CD151 scFv-Fc Chimera (VS-0325-FY33) (CAT#: VS-0325-FY33)
The anti-CD151 scFv-Fc antibody targets CD151, a tetraspanin protein involved in cell adhesion, migration, and cancer progression. It is useful for studying the role of CD151 in tumor biology, metastasis, and cell signaling.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2428/6397_B_7_5.jpg

(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2428/6397_A_7_3.jpg

(Cholangiocytes
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2428/6397_A_7_4.jpg

(Cells in glomeruli
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2428/6397_A_8_5.jpg

(Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2428/6397_A_7_8.jpg
Specifications
- Immunogen
- CD151-Integrin α6β1-KLH complex protein (GQRDHASNIYKVEGGC-KLH).
- Host Species
- Mouse
- Type
- Mouse IgG1, scFv-Fc
- Specificity
- Human CD151
- Species Reactivity
- Human
- Applications
- Western Blot, Immunoprecipitation, Immunohistochemistry, Immunofluorescence
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- CD151 Molecule (Raph Blood Group); CD151 Antigen; Platelet-Endothelial Tetraspan Antigen 3; CD151 Antigen (Raph Blood Group); Membrane Glycoprotein SFA-1; Tetraspanin-24; Tspan-24; TSPAN24; PETA-3
- Gene ID
- 977
- UniProt ID
- P48509
- Long Name
- CD151 Molecule (Raph Blood Group)
- Sequence Similarities
- Belongs to the tetraspanin (TM4SF) family.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Palmitoylated.
Palmitoylation by ZDHHC2 regulates CD151 expression, association with other tetraspanin family proteins and function in cell adhesion.
Ubiquitinated by RNF128 on lysine residues present in the tetraspanin amino terminus via 'Lys-48'-linked ubiquitin leading to proteasomal degradation.
Glycosylation at Asn159
Ubiquitination at Lys249
Modification sites at PhosphoSitePlus
- Protein Refseq
- XP_024304548.1; XP_054226609.1; NP_001034579.1; NP_004348.2; NP_620598.1
- Function
- CD151 is a tetraspanin protein that plays a pivotal role in cell adhesion, migration, and tumor metastasis. It forms complexes with integrins and other membrane proteins, influencing cell-matrix interactions and signaling pathways. CD151 is essential for tissue development and homeostasis, and its aberrant expression is associated with various pathological conditions, including cancer. It effects things such as cell motility, and also tumor growth.
Recommended Products
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CD151"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1623z | Mouse Anti-CD151 Recombinant Antibody (clone 24G4) | WB, FC, ICC, IHC, FuncS | Mouse IgG1 |
MOB-0383CT | Mouse Anti-CD151 Recombinant Antibody (clone 22H6b) | ELISA, FC, IF, IHC-Fr, IHC-P, IP, WB | Mouse IgG1 |
HPAB-0212-CN | Mouse Anti-CD151 Recombinant Antibody (HPAB-0212-CN) | FC, IP, IHC, IF, Inhib, WB | Mouse IgG |
HPAB-0213-CN | Mouse Anti-CD151 Recombinant Antibody (HPAB-0213-CN) | IF, FuncS, IB, WB, FC, IHC, IP | Mouse IgG |
HPAB-0214-CN | Mouse Anti-CD151 Recombinant Antibody (clone 9B) | WB, Co-IP, IF, IHC, Inhib, FuncS, FC, ELISA | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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