Mouse Anti-CD151 scFv-Fc Chimera (VS-0325-FY33)
CAT#: VS-0325-FY33
The anti-CD151 scFv-Fc antibody targets CD151, a tetraspanin protein involved in cell adhesion, migration, and cancer progression. It is useful for studying the role of CD151 in tumor biology, metastasis, and cell signaling.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2428/6397_B_7_5.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2428/6397_A_7_3.jpg
Normal Tissue
Figure 3 Liver
Cholangiocytes
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2428/6397_A_7_4.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2428/6397_A_8_5.jpg
Normal Tissue
Figure 5 Lymph node
Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2428/6397_A_7_8.jpg
❮
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Specifications
- Immunogen
- CD151-Integrin α6β1-KLH complex protein (GQRDHASNIYKVEGGC-KLH).
- Host Species
- Mouse
- Type
- Mouse IgG1, scFv-Fc
- Specificity
- Human CD151
- Species Reactivity
- Human
- Applications
- Western Blot, Immunoprecipitation, Immunohistochemistry, Immunofluorescence
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- CD151 Molecule (Raph Blood Group); CD151 Antigen; Platelet-Endothelial Tetraspan Antigen 3; CD151 Antigen (Raph Blood Group); Membrane Glycoprotein SFA-1; Tetraspanin-24; Tspan-24; TSPAN24; PETA-3
- Gene ID
- 977
- UniProt ID
- P48509
- Long Name
- CD151 Molecule (Raph Blood Group)
- Sequence Similarities
- Belongs to the tetraspanin (TM4SF) family.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Palmitoylated.
Palmitoylation by ZDHHC2 regulates CD151 expression, association with other tetraspanin family proteins and function in cell adhesion.
Ubiquitinated by RNF128 on lysine residues present in the tetraspanin amino terminus via 'Lys-48'-linked ubiquitin leading to proteasomal degradation.
Glycosylation at Asn159
Ubiquitination at Lys249
Modification sites at PhosphoSitePlus
- Protein Refseq
- XP_024304548.1; XP_054226609.1; NP_001034579.1; NP_004348.2; NP_620598.1
- Function
- CD151 is a tetraspanin protein that plays a pivotal role in cell adhesion, migration, and tumor metastasis. It forms complexes with integrins and other membrane proteins, influencing cell-matrix interactions and signaling pathways. CD151 is essential for tissue development and homeostasis, and its aberrant expression is associated with various pathological conditions, including cancer. It effects things such as cell motility, and also tumor growth.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
See other products for "CD151"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1605CL | Anti-Human CD151 Recombinant Antibody (c203B6) | ELISA, FC, WB | Chimeric antibody (mouse/human) |
| TAB-1606CL | Anti-Human CD151 Recombinant Antibody (c214B2) | ELISA, FC, WB, Block, FuncS | Chimeric antibody (mouse/human) |
| TAB-1605CL-S(P) | Anti-Human CD151 Recombinant Antibody scFv Fragment (c203B6) | ELISA, FC, WB | Chimeric antibody (mouse/human) |
| TAB-1606CL-S(P) | Anti-Human CD151 Recombinant Antibody scFv Fragment (c214B2) | ELISA, FC, WB, Block, FuncS | Chimeric antibody (mouse/human) |
| TAB-1605CL-F(E) | Anti-Human CD151 Recombinant Antibody Fab Fragment (c203B6) | ELISA, FC, WB | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1607CL | Anti-Human CD151 Recombinant Antibody (Humanized 203B6) | FC, FuncS, WB | Humanized antibody |
| TAB-1608CL | Anti-Human CD151 Recombinant Antibody (Humanized 214B2) | FC, FuncS, WB | Humanized antibody |
| TAB-1607CL-S(P) | Anti-Human CD151 Recombinant Antibody scFv Fragment (Humanized 203B6) | FC, FuncS, WB | Humanized antibody |
| TAB-1607CL-F(E) | Anti-Human CD151 Recombinant Antibody Fab Fragment (Humanized 203B6) | FC, FuncS, WB | Humanized antibody |
| TAB-1608CL-F(E) | Anti-Human CD151 Recombinant Antibody Fab Fragment (Humanized 214B2) | FC, FuncS, WB | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1601CL-S(P) | Anti-Human CD151 Recombinant Antibody scFv Fragment (203B6) | FC, FuncS | |
| TAB-1601CL-F(E) | Anti-Human CD151 Recombinant Antibody Fab Fragment (203B6) | FC, FuncS | |
| TAB-1602CL-F(E) | Anti-Human CD151 Recombinant Antibody Fab Fragment (205H8) | FC, FuncS | |
| TAB-1603CL-F(E) | Anti-Human CD151 Recombinant Antibody Fab Fragment (211F3) | FC, FuncS | |
| TAB-1604CL-F(E) | Anti-Human CD151 Recombinant Antibody Fab Fragment (214B2) | FC, FuncS |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0383CT | Mouse Anti-CD151 Recombinant Antibody (clone 22H6b) | ELISA, FC, IF, IHC-Fr, IHC-P, IP, WB | Mouse IgG1 |
| HPAB-0212-CN | Mouse Anti-CD151 Recombinant Antibody (HPAB-0212-CN) | FC, IP, IHC, IF, Inhib, WB | Mouse IgG |
| HPAB-0213-CN | Mouse Anti-CD151 Recombinant Antibody (HPAB-0213-CN) | IF, FuncS, IB, WB, FC, IHC, IP | Mouse IgG |
| HPAB-0214-CN | Mouse Anti-CD151 Recombinant Antibody (clone 9B) | WB, Co-IP, IF, IHC, Inhib, FuncS, FC, ELISA | Mouse IgG1 |
| FAMAB-1034CQ | Human Anti-CD151 Recombinant Antibody (clone 11G5a) | IP, FC, FuncS, IHC | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-285CQ | Mouse Anti-CD151 Recombinant Antibody (clone 50-6) | FC, ICC, WB, Block | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0533 | Hi-Affi™ Rabbit Anti-CD151 Recombinant Antibody (clone DS533AB) | WB, IHC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0212-CN-S(P) | Mouse Anti-CD151 Recombinant Antibody scFv Fragment (HPAB-0212-CN-S(P)) | WB, FC, IHC, IP | Mouse scFv |
| HPAB-0213-CN-S(P) | Mouse Anti-CD151 Recombinant Antibody scFv Fragment (HPAB-0213-CN-S(P)) | WB, FC, IHC, IP | Mouse scFv |
| HPAB-0214-CN-S(P) | Mouse Anti-CD151 Recombinant Antibody (clone 9B); scFv Fragment | WB, ELISA, IHC, IF, Co-IP | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0212-CN-F(E) | Mouse Anti-CD151 Recombinant Antibody Fab Fragment (HPAB-0212-CN-F(E)) | WB, FC, IHC, IP | Mouse Fab |
| HPAB-0213-CN-F(E) | Mouse Anti-CD151 Recombinant Antibody Fab Fragment (HPAB-0213-CN-F(E)) | WB, FC, IHC, IP | Mouse Fab |
| HPAB-0214-CN-F(E) | Mouse Anti-CD151 Recombinant Antibody (clone 9B); Fab Fragment | WB, ELISA, IHC, IF, Co-IP | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY18 | CytoStream™ Mouse Anti-CD151 Recombinant Antibody (VS-0225-XY18) | FC, IHC, IP | Mouse IgG1, kappa |
| VS-0225-XY19 | CytoStream™ Rat Anti-CD151 Recombinant Antibody (VS-0225-XY19) | FC | Rat IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY352 | Anti-CD151 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC232 | Recombinant Anti-CD151 Vesicular Antibody, EV Displayed (VS-0425-YC232) | ELISA, FC, Cell-uptake |
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