Mouse Anti-CR1 Recombinant Antibody (clone 4AE11) (CAT#: VS3-XY515)

1. Q 1: What diseases are related to the CR1 that this antibody targets?

   A: CR1 is associated with various diseases such as systemic lupus erythematosus and malaria. While this antibody is intended for research, it can help in uncovering the molecular mechanisms related to these diseases by studying alterations in CR1 expression and function.

2. Q 2: Is this antibody effective in flow cytometry applications?

   A: Yes, the Mouse Anti-CR1 Recombinant Antibody (clone 4AE11) is effective in flow cytometry. It enables the analysis of CR1 expression on the surface of live or fixed cells, allowing researchers to quantify and profile cell populations expressing this receptor.

3. Q 3: What makes clone 4AE11 distinct from other CR1 antibodies?

   A: Clone 4AE11 is distinct due to its recombinant production, ensuring high reproducibility and specificity. This particular clone has been optimized for various applications like IF and flow cytometry, making it versatile for different experimental needs.

4. Q 4: Is the antibody reactive with species other than mouse?

   A: While optimized for mouse, the cross-reactivity of the Mouse Anti-CR1 Recombinant Antibody (clone 4AE11) with other species depends on the conservation of the CR1 antigen epitope. Researchers should verify its reactivity with non-mouse CR1 via preliminary experiments.

5. Q 5: Can it be used to study CR1 function in immune pathways?

   A: Yes, the antibody is instrumental in studying CR1's role in immune pathways. Through applications like cell signaling assays and co-localization studies, researchers can investigate how CR1 contributes to immune responses, providing insights into its functional relevance.

View the frequently asked questions answered by Creative Biolabs Support.