Mouse Anti-IL2RB (clone A41) scFv-Fc Chimera (CAT#: VS-0325-FY115)
The anti-CD122 scFv-Fc antibody targets CD122, a subunit of the IL-2 and IL-15 receptors, which is critical for lymphocyte activation and proliferation. It is useful for studying the role of CD122 in immune cell signaling and regulation.
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Normal Tissue
RNA Expression
Figure 1 Bone marrow
(Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62657/139408_B_5_4.jpg
(Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62657/139408_B_5_4.jpg
Figure 2 Lymph node
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62657/139408_A_8_8.jpg
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62657/139408_A_8_8.jpg
Figure 3 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000100385-IL2RB
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000100385-IL2RB
Figure 3 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000100385-IL2RB
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000100385-IL2RB
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG1, scFv-Fc
- Specificity
- Human IL2RB
- Species Reactivity
- Human
- Clone
- A41
- Applications
- Inhibition
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Interleukin 2 Receptor Subunit Beta
- Gene ID
- 3560
- UniProt ID
- P14784
- Long Name
- Interleukin 2 Receptor Subunit Beta
- Sequence Similarities
- Belongs to the type I cytokine receptor family. Type 4 subfamily.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Glycosylation at Asn29, Asn43, Asn71, and Asn149
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen
- Protein Refseq
- NP_000869.1; NP_001333151.1; NP_001333152.1
- Function
- IL2RB (Interleukin 2 receptor subunit beta) is a component of the IL-2 receptor complex, which is crucial for T cell proliferation and activation. It plays a vital role in immune regulation and is a target for immunotherapy.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1173z | Mouse Anti-IL2RB Recombinant Antibody (clone 40D9) | FC, IP, FuncS | Mouse IgG1 |
| MOB-1587MZ | Recombinant Mouse Anti-Human IL2RB Antibody (clone 38403.2) | ELISA, Neut, WB | Mouse antibody |
| HPAB-0249CQ | Mouse Anti-IL2RB Recombinant Antibody (clone MIK-BETA 1) | FC, Inhib, FuncS | Mouse IgG2a |
| FN-027CQ | Mouse Anti-IL2RB Recombinant Antibody (clone 9A2) | FC, FuncS | Mouse IgG2a, κ |
| HPAB-2114-FY | Mouse Anti-IL2RB Recombinant Antibody (clone MAKA41) | Inhib | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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