Recombinant Mouse Anti-MAGEA8 Soluble TCR (A31C2-B32G3) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF492)
Mouse TCR (A31C2-B32G3) recognizes MAGEA8 peptide (KVAELVHFL) in the context of HLA-A*0201. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Mouse soluble TCR (A31C2-B32G3). Please note that the activity is not guaranteed.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Colon
(Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3998/12407_A_7_3.jpg
(Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3998/12407_A_7_3.jpg
Figure 2 Kidney
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3998/12407_A_8_5.jpg
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3998/12407_A_8_5.jpg
Figure 3 Testis
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3998/12407_A_4_6.jpg
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3998/12407_A_4_6.jpg
Figure 4 Placenta
(Cytotrophoblasts Staining: Medium Intensity: Moderate Quantity:>75% Decidual cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Hofbauer cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Syncytiotrophoblasts - cell body Staining: Medium Intensity: Moderate Quantity: 75%-25% Syncytiotrophoblasts - microvilli Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3998/12407_A_2_7.jpg
(Cytotrophoblasts Staining: Medium Intensity: Moderate Quantity:>75% Decidual cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Hofbauer cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Syncytiotrophoblasts - cell body Staining: Medium Intensity: Moderate Quantity: 75%-25% Syncytiotrophoblasts - microvilli Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3998/12407_A_2_7.jpg
Figure 5 RNA cell line category: Group enriched (U-2 OS, U-266/70)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000156009-MAGEA8
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000156009-MAGEA8
Specifications
- Host Species
- Mouse
- Target
- MAGEA8
- Species Reactivity
- Human
- Epitope
- KVAELVHFL
- MHC
- HLA-A*0201
- Clone
- A31C2-B32G3
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- Related Disease
- Melanoma
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1145CT | Recombinant Mouse anti-Human MAGEA8 Monoclonal antibody (EML568) | WB |
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