Recombinant Mouse Anti-Mbp Soluble TCR (Tg4) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF520)
Mouse TCR (Tg4) recognizes Mbp peptide (ASQKRPSQR) in the context of H2 class II. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Mouse soluble TCR (Tg4). Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/64368/1577_H5_1_selected.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/64368/1577_H5_1_selected.jpg
Figure 2 Cerebral cortex
(Endothelial cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous
nuclear
Neuropil
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2300/6024_B_9_5.jpg
(Endothelial cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous
nuclear
Neuropil
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2300/6024_B_9_5.jpg
Figure 3 Caudate
(Glial cells
Staining:
High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2300/6024_B_8_7.jpg
(Glial cells
Staining:
High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2300/6024_B_8_7.jpg
Figure 4 RNA cell line category: Cell line enhanced (HL-60, SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197971-MBP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197971-MBP
Figure 4 RNA cell line category: Cell line enhanced (HL-60, SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197971-MBP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197971-MBP
Specifications
- Host Species
- Mouse
- Target
- Mbp
- Species Reactivity
- Mouse
- Epitope
- ASQKRPSQR
- MHC
- H2 class II
- Clone
- Tg4
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- Related Disease
- Autoimmune Disease
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
Related Resources
Asthma
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-174LC | Recombinant Anti-MBP Antibody (Non-glycosylated) | ELISA | Mouse antibody |
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