Recombinant Mouse Anti-Type II Collagen Soluble TCR (qCII85.33) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF884)
Mouse TCR (qCII85.33) recognizes Type II Collagen peptide (IAGFKGEQ) in the context of H2-IAq. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Mouse soluble TCR (qCII85.33). Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEK 293
(Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/55753/1472_C7_4_selected.jpg
(Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/55753/1472_C7_4_selected.jpg
Figure 2 IHC staining of human cartilage
(Immunohistochemical staining of human cartilage shows moderate cytoplasmic positivity in the chondrocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/ih_additional_tissue/2214/1552_866_400x400.jpg
(Immunohistochemical staining of human cartilage shows moderate cytoplasmic positivity in the chondrocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/ih_additional_tissue/2214/1552_866_400x400.jpg
Figure 3 Cerebral cortex
(Neuronal cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2214/169753_B_7_5.jpg
(Neuronal cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2214/169753_B_7_5.jpg
Figure 4 RNA cell line category: Cell line enhanced (AF22, HAP1, HEK93)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000139219-COL2A1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000139219-COL2A1
Specifications
- Host Species
- Mouse
- Target
- Type II Collagen
- Species Reactivity
- Bos taurus
- Epitope
- IAGFKGEQ
- MHC
- H2-IAq
- Clone
- qCII85.33
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- Related Disease
- Lung malignancy
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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