Perfusion technology has gained traction as a transformative approach within the biotechnology industry. Unlike traditional batch processing, perfusion culture involves the continuous removal of waste and replenishment of fresh nutrients, thereby maintaining a stable environment conducive to high cell densities and product consistency over prolonged periods. This constant renewal facilitates higher cell densities and prolonged cell viability, ultimately leading to greater product yields. Creative Biolabs integrates cutting-edge perfusion technology to enhance upstream process intensification, achieving yields that exceed traditional methods.

Benefits of Perfusion in Antibody Production

Our Perfusion Process Development Service

At Creative Biolabs, our perfusion process development service integrates advanced techniques and expertise to deliver high-quality antibodies tailored to meet the specific needs of our clients. We utilize state-of-the-art equipment and methodologies to refine and optimize production processes, ensuring maximum yield and efficiency. Our perfusion process development service not only boosts productivity but also offers scalable solutions for clinical and commercial manufacturing needs. Our experienced team offers end-to-end support, guiding clients through every stage of antibody development.

Cutting-edge Technology and Equipment

At Creative Biolabs, our facilities are equipped with cutting-edge bioreactor systems that provide precise control over culture conditions. These advanced systems allow for continuous media exchange and maintain optimal conditions for high cell density and viability, including crucial parameters like temperature, pH, and nutrient levels. By leveraging cell retention technologies like the alternating tangential flow system, we effectively address challenges such as filter fouling, ensuring smooth and uninterrupted production cycles. We use sophisticated analytical tools to monitor and control critical parameters throughout the perfusion process. These tools enable real-time data collection and analysis, ensuring that we maintain high standards of quality and consistency.

Advantages

• Superior Yield and Quality: By harnessing high-density cell cultures, our perfusion processes achieve product titers that surpass those of conventional fed-batch methods by tenfold.
• Flexibility and Adaptability: Our perfusion systems are designed to be highly adaptable, accommodating different cell lines and production scales. Whether you're transitioning from fed-batch to perfusion or enhancing an existing perfusion process, Creative Biolabs provides customizable solutions to meet your unique production goals.
• Large-scale production Ability: Creative Biolabs offers up to 200L perfusion GMP capacity, enabling large-scale production of high-quality antibodies under stringent GMP conditions. This capacity allows us to meet the demands of commercial manufacturing while maintaining the flexibility to adapt to various production scales as needed.

For research use only. Not intended for any clinical use.