Pyroptosis Antibody Panel (CASP1, GSDMD, IL1B, TUBB1)
CAT#: VS-0725-YC18
The Pyroptosis Antibody Panel are sets of 4 antibodies, enabling the simultaneous detection of key proteins involved in this crucial pathway. Our comprehensive set includes antibodies against CASP1, GSDMD, IL1B, and TUBB1. This panel provides a streamlined approach for investigating inflammatory diseases and host-pathogen interactions, ensuring precise and reproducible results for your cutting-edge studies.
| Sub Cat | Component Name | Clone | Type | Target | Species Reactivity | Applications | |
| VS3-CJ857 | Rabbit Anti-CASP1 Recombinant Antibody (VS3-CJ857) | Rabbit IgG | CASP1 | Human, Mouse, Rat | WB, IHC, FC | ||
| VS3-QX1198 | Mouse Anti-TUBB1 Recombinant Antibody (clone 1F10-B7-E4) | 1F10-B7-E4 | Mouse IgG1 | TUBB1 | Human, Mouse, Monkey, Rat | WB, IHC, ICC, FC, ELISA | |
| TAB-021 | Anti-Human IL1Beta Recombinant Antibody (Canakinumab) | IgG1 - kappa | IL1 beta | Human | Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, IHC and most other immunological methods. | ||
| VS-0725-YC128 | Rabbit Anti-GSDMD Polyclonal Antibody | Rabbit IgG | GSDMD | Human, Mouse, Rat | ICC, IF, WB |
More Infomation
Specifications
- Targets
- CASP1, GSDMD, IL1B, TUBB1
- Species Reactivity
- Human
- Research Area
- Pyroptosis
- Introduction
- Pyroptosis is a distinct form of regulated cell death (RCD) that is inherently pro-inflammatory. Unlike apoptosis, which is typically a quiet and immunologically silent demise, pyroptosis is characterized by cellular swelling, pore formation in the plasma membrane, and eventual cell lysis, leading to the rapid release of pro-inflammatory intracellular contents into the extracellular space. This lytic expulsion of cellular material, including various danger-associated molecular patterns (DAMPs) and processed cytokines, actively amplifies the inflammatory response.
- Storage
- Store at 4°C for up to a week. For long-term storage, store at -20°C or below.
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