Qa-1b/Human Hsp60 (GMKFDRGYI) MHC Monomer
CAT#: MHC-YF309
This product is a MHC monomer of biotinylated peptide/MHC complex composed Hsp60-derived peptide of GMKFDRGYI sequence and Qa-1b molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to mitochondria.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1523/if_selected.jpg
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Specifications
- Allele
- Qa-1b
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- Hsp60
- Antigen Species
- Human
- Peptide
- GMKFDRGYI
- Conjugate
- Biotin
- Application
- MHC Multimer
Target
- Antigen Introduction
- This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
- Alternative Names
- HLD4; CPN60; GROEL; HSP60; HSP65; SPG13; HSP-60; HuCHA60
- Gene ID
- 3329
- UniProt ID
- P10809
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Datasheet
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COA
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