Recombinant Anti-ADAM9 Vesicular Antibody, EV Displayed (VS-0425-YC453) (CAT#: VS-0425-YC453)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• ADAM9

• Host Animal
• Human

• Antibody Isotype
• IgG

• Species Reactivity
• Human, Cynomolgus

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• ADAM metallopeptidase domain 9

• Molecular Function
• Hydrolase, Metalloprotease, Protease

• Cellular Localization
• Vesicles, Endoplasmic reticulum

• Introduction
• This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene.

• Alternative Names
• CORD9, KIAA0021, MCMP, MDC9, Mltng

• Gene ID
• 8754

• UniProt ID
• Q13443

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