Recombinant Anti-ADCYAP1R1 Vesicular Antibody, EV Displayed (VS-0425-YC565)

CAT#: VS-0425-YC565

The Recombinant Anti-ADCYAP1R1 Vesicular Antibody, EV Displayed (VS-0425-YC565) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ADCYAP1R1-expressed cells or tissues. ADCYAP1R1 is a receptor mediating adenylate cyclase activation, influencing diverse biological processes.

Gene Expression
Figure 1 IF staining of human cell line SH-SY5Y Figure 2 High expression in cerebral cortex Figure 3 Colon Figure 4 Kidney Figure 5 Testis Figure 6 RNA cell line category: Cell line enhanced (AF22, NTERA-2, SCLC-21H, SH-SY5Y)

Recombinant Antibody

  • Application
  • ELISA, FC, Neut, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • ADCYAP1R1
  • Host Animal
  • Human
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • z domain
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Binding Affinity
  • Kd = 0.85 µg/mL
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • ADCYAP receptor type I
  • Biological Process
  • Differentiation, Spermatogenesis
  • Molecular Function
  • Developmental protein, G-protein coupled receptor, Receptor, Transducer
  • Cellular Localization
  • Vesicles
  • Introduction
  • This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010]
  • Alternative Names
  • PAC1, PAC1R, PACAPR
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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