Recombinant Anti-ADCYAP1R1 Vesicular Antibody, EV Displayed (VS-0425-YC565) (CAT#: VS-0425-YC565)
The Recombinant Anti-ADCYAP1R1 Vesicular Antibody, EV Displayed (VS-0425-YC565) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ADCYAP1R1-expressed cells or tissues. ADCYAP1R1 is a receptor mediating adenylate cyclase activation, influencing diverse biological processes.

(Immunofluorescent staining of human cell line SH-SY5Y shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/30739/1735_E10_1_selected.jpg

(Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_B_7_5.jpg

(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_A_9_3.jpg

(Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_A_9_5.jpg

(Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_A_4_6.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000078549-ADCYAP1R1
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ADCYAP1R1
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- ADCYAP receptor type I
- Biological Process
- Differentiation, Spermatogenesis
- Molecular Function
- Developmental protein, G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Vesicles
- Introduction
- This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010]
- Alternative Names
- PAC1, PAC1R, PACAPR
- Gene ID
- 117
- UniProt ID
- P41586
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "ADCYAP1R1"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0917CL | Anti-Human ADCYAP1R1 Recombinant Antibody (2C) | Competitive ELISA | |
TAB-0917CL-S(P) | Anti-Human ADCYAP1R1 Recombinant Antibody scFv Fragment (2C) | Competitive ELISA | |
TAB-0917CL-F(E) | Anti-Human ADCYAP1R1 Recombinant Antibody Fab Fragment (2C) | Competitive ELISA |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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