Recombinant Anti-ADGRG2 Vesicular Antibody, EV Displayed (VS-0425-YC632) (CAT#: VS-0425-YC632)
The Recombinant Anti-ADGRG2 Vesicular Antibody, EV Displayed (VS-0425-YC632) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ADGRG2-expressed cells or tissues. ADGRG2 is an epididymis-specific G protein-coupled receptor, with potential proteolytic processing indicated by a scission motif.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1478/54_A11_2_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1478/54_A11_2_selected.jpg

Figure 2 High expression in epididymis
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1478/161279_A_3_6_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1478/161279_A_3_6_selected.jpg

Figure 3 Low expression in endometrium 1
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1478/161279_B_5_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1478/161279_B_5_3_val_selected.jpg

Figure 4 Cerebral cortex
(Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50029/161215_B_9_5.jpg
(Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50029/161215_B_9_5.jpg

Figure 5 Epididymis
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50029/161215_A_2_6.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/50029/161215_A_2_6.jpg

Figure 6 RNA cell line category: Cell line enhanced (A549, BEWO, HeLa, NTERA-2, RPMI-8226, SH-SY5Y, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000173698-ADGRG2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000173698-ADGRG2
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ADGRG2
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Adhesion G protein-coupled receptor G2
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Plasma membrane, Cytosol
- Introduction
- This gene encodes a member of the G protein-coupled receptor family described as an epididymis-specific transmembrane protein. The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family (PMID: 11973329). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
- Alternative Names
- EDDM6, GPR64, HE6, TM7LN2
- Gene ID
- 10149
- UniProt ID
- Q8IZP9
Downloads
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See other products for "ADGRG2"
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Mouse Antibody Products
IgG Antibody Products
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ScFv Antibody Products
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-001CT | Mouse Anti-ADGRG2 Recombinant Antibody (TAB-001CT) | WB | Mouse IgG |
TAB-001CT-S(P) | Mouse Anti-ADGRG2 Recombinant Antibody; scFv Fragment (TAB-001CT-S(P)) | WB | Mouse scFv |
TAB-001CT-F(E) | Mouse Anti-ADGRG2 Recombinant Antibody; Fab Fragment (TAB-001CT-F(E)) | WB | Mouse Fab |
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