Recombinant Anti-BEST1 Vesicular Antibody, EV Displayed (VS-0425-YC413)
CAT#: VS-0425-YC413
The Recombinant Anti-BEST1 Vesicular Antibody, EV Displayed (VS-0425-YC413) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to BEST1-expressed cells or tissues. The BEST1 is part of the bestrophin family, linked to chloride ion channel formation, with mutations causing macular dystrophies.
Gene Expression
Normal Tissue
Figure 1 Low expression in liver
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57464/136112_A_7_4_val_selected.jpg
Normal Tissue
Figure 2 Testis
Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/57464/136112_A_4_6.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enriched (SK-MEL-30)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167995-BEST1
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- BEST1
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Chicken
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Bestrophin 1
- Biological Process
- Ion transport, Sensory transduction, Transport, Vision
- Molecular Function
- Chloride channel, Ion channel
- Introduction
- This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008]
- Gene ID
- 423124
- UniProt ID
- A0A8V0ZZU7
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC413. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "BEST1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-023 | Mouse Anti-BEST1 Recombinant Antibody (clone 10D10) | WB, Neut, FuncS | Mouse IgG1 |
| PABL-410 | Recombinant Human Anti-BEST1 Antibody | WB, ELISA, FuncS | IgG |
| MOB-0253CT | Mouse Anti-BEST1 Recombinant Antibody (clone F7-7) | IF, IHC-Fr, IP, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-023 | Mouse Anti-BEST1 Recombinant Antibody (clone 10D10); scFv Fragment | WB, Neut, FuncS | Mouse scFv |
| PSBL-407 | Recombinant Human Anti-BEST1 Antibody scFv Fragment | WB, ELISA, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-023 | Mouse Anti-BEST1 Recombinant Antibody (clone 10D10); Fab Fragment | WB, Neut, FuncS | Mouse Fab |
| PFBL-407 | Recombinant Human Anti-BEST1 Antibody Fab Fragment | WB, ELISA, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY49 | Mouse Anti-NHP BEST1 Recombinant Antibody (clone E6-6) | WB | Mouse IgG1, kappa |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: FuncS, Inhib, IP, ELISA
-3-1.png)
Application: ELISA, PD, Activ, PK, Stim
-4.jpg)
Application: FC
Application: FC
Application: ELISA, IHC, IF, IP
Application: ELISA, FuncS, RIA, IP, IF, IHC, IA, Block
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
