Recombinant Anti-BST2 Vesicular Antibody, EV Displayed (VS-0425-YC255)
CAT#: VS-0425-YC255
The Recombinant Anti-BST2 Vesicular Antibody, EV Displayed (VS-0425-YC255) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to BST2-expressed cells or tissues. The BST2 is a bone marrow stromal cell antigen involved in B-cell growth, potentially related to rheumatoid arthritis.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SiHa
Immunofluorescent staining of human cell line SiHa shows localization to the Golgi apparatus & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/73472/1920_E3_7_cr5cc2b8004d589_selected.jpg
Normal Tissue
Figure 2 Adrenal gland
High expression in adrenal gland
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17060/39065_B_4_5_val_selected.jpg
Normal Tissue
Figure 3 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17060/39065_A_9_8.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17060/39065_B_9_5.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17060/39065_A_9_3.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17060/39065_A_8_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17060/39065_A_6_6.jpg
Normal Tissue
Figure 8 Placenta
Decidual cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Trophoblastic cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/17060/39065_A_1_7.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (BJ hTERT+ SV40 Large T+ RasG12V, Karpas-707)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130303-BST2
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- BST2
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Bone marrow stromal cell antigen 2
- Biological Process
- Antiviral defense, B-cell activation, Host-virus interaction, Immunity, Innate immunity
- Cellular Localization
- Golgi apparatus, Vesicles
- Introduction
- Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis.
- Alternative Names
- BST-2, CD317, HM1.24, tetherin
- Gene ID
- 684
- UniProt ID
- Q10589
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Datasheet
MSDS
COA
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See other products for "BST2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G002E | Anti-BST2 immunotoxin (scFv)-PE | Cytotoxicity assay, Function study |
| CAT | Product Name | Application | Type |
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| TAB-1295CL | Human Anti-BST2 Recombinant Antibody (TAB-1295CL) | Cyt, FC | Humanized IgG1 |
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| TAB-1298CL-S(P) | Anti-Human BST2 Recombinant Antibody scFv Fragment | ELISA | Humanized antibody |
| TAB-1295CL-F(E) | Human Anti-BST2 Recombinant Antibody; Fab Fragment (TAB-1295CL-F(E)) | FC | Humanized Fab |
| TAB-1298CL-F(E) | Anti-Human BST2 Recombinant Antibody Fab Fragment | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1297CL | Chimeric Anti-Human BST2 Recombinant Antibody | ELISA | Chimeric antibody (mouse/human) |
| TAB-1297CL-S(P) | Chimeric Anti-Human BST2 Recombinant Antibody scFv Fragment | ELISA | Chimeric antibody (mouse/human) |
| TAB-1297CL-F(E) | Chimeric Anti-Human BST2 Recombinant Antibody Fab Fragment | ELISA | Chimeric antibody (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC143 | PE-A*02:01/Human HM1.24 (KLQDASAEV) MHC Tetramer | FCM | |
| MHC-LC144 | APC-A*02:01/Human HM1.24 (KLQDASAEV) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-072CQ | Mouse Anti-BST2 Recombinant Antibody (clone 26F8) | FC, FuncS, Neut | Mouse IgG1, κ |
| NEUT-073CQ | Rat Anti-Bst2 Recombinant Antibody (VMC170) | Neut, FC, IF, IHC, IHC-Fr, IHC-P | Rat IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0390 | Hi-Affi™ Rabbit Anti-BST2 Recombinant Antibody (clone DS390AB) | WB, IHC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0026-YC-S(P) | Mouse Anti-BST2 Recombinant Antibody (clone 1C12C6); scFv Fragment | ELISA, WB, IHC | Mouse scFv |
| HPAB-1004-FY-F(E) | Mouse Anti-BST2 Recombinant Antibody (clone 4LD); scFv Fragment | FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0026-YC-F(E) | Mouse Anti-BST2 Recombinant Antibody (clone 1C12C6); Fab Fragment | ELISA, WB, IHC | Mouse Fab |
| HPAB-1004-FY-S(P) | Human Anti-BST2 Recombinant Antibody (clone 4LD); Fab Fragment | FC | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC926 | AbPlus™ Anti-BST2 Magnetic Beads (VS-0724-YC926) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY844 | Anti-BST2 Immunohistochemistry Kit | IHC |
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