Recombinant Anti-BTLA Vesicular Antibody, EV Displayed (VS-0425-YC609) (CAT#: VS-0425-YC609)
The Recombinant Anti-BTLA Vesicular Antibody, EV Displayed (VS-0425-YC609) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to BTLA-expressed cells or tissues. BTLA is a receptor transmitting immune-suppressing signals, with alternatively spliced variants. Polymorphisms may increase rheumatoid arthritis risk.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human spleen
(Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in a subset of cells in red pulp.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47211/ihc_selected.jpg
(Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in a subset of cells in red pulp.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47211/ihc_selected.jpg
Figure 2 Tonsil
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62029/ihc_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62029/ihc_selected.jpg
Figure 3 Lymph node
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62029/148776_A_8_8.jpg
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62029/148776_A_8_8.jpg
Figure 4 RNA cell line category: Cell line enhanced (U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000186265-BTLA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000186265-BTLA
Recombinant Antibody
- Application
- ELISA, FC, SPR, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- BTLA
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- B and T lymphocyte associated
- Biological Process
- Adaptive immunity, Immunity
- Molecular Function
- Receptor
- Introduction
- This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011]
- Alternative Names
- BTLA1, CD272
- Gene ID
- 151888
- UniProt ID
- Q7Z6A9
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1309CL | Human Anti-BTLA Recombinant Antibody (TAB-1309CL) | Inhib | Human IgG |
| TAB-1310CL | Human Anti-BTLA Recombinant Antibody (TAB-1310CL) | Block | Human IgG |
| TAB-1309CL-F(E) | Human Anti-BTLA Recombinant Antibody; Fab Fragment (TAB-1309CL-F(E)) | ELISA | Human Fab |
| TAB-1310CL-F(E) | Human Anti-BTLA Recombinant Antibody; Fab Fragment (TAB-1310CL-F(E)) | ELISA | Human Fab |
| TAB-1311CL-F(E) | Human Anti-BTLA Recombinant Antibody; Fab Fragment (TAB-1311CL-F(E)) | ELISA | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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