Recombinant Rabbit Anti-CCL4 Detection Antibody (clone R08-5V7)

CAT#: VS3-WK1793

This antibody is a rabbit recombinant antibody against human CCL4. It was developed by immunization of rabbit with recombinant human CCL4 protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. R06-2O6 and R08-5V7 were identified as antibody pair for sandwich ELISA. As a detection antibody, the clone R08-5V7 can be used in ELISA analysis to identify human CCL4.

Gene Expression
Figure 1 Cerebral cortex Figure 2 Testis

Specifications

  • Immunogen
  • Recombinant human CCL4 protein
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human CCL4
  • Species Reactivity
  • Human
  • Clone
  • R08-5V7
  • Applications
  • ELISA
  • Conjugate
  • Unconjugated

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Protein A affinity purified
  • Purity
  • >95% as determined by SDS-PAGE
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • 0.01M PBS, pH 7.2
  • Storage
  • Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
  • Shipping
  • Ice packs

Target

  • Alternative Names
  • C-C Motif Chemokine Ligand 4; Small Inducible Cytokine A4 (Homologous To Mouse Mip-1b); Macrophage Inflammatory Protein 1-Beta; Lymphocyte Activation Gene 1 Protein; G-26 T-Lymphocyte-Secreted Protein; Chemokine (C-C Motif) Ligand 4; T-Cell Activation Protein 2; MIP-1-Beta(1-69); MIP-1-Beta; SIS-Gamma; PAT 744; SCYA4; LAG-1; MIP1B
  • Long Name
  • C-C Motif Chemokine Ligand 4
  • Sequence Similarities
  • Belongs to the intercrine beta (chemokine CC) family.
  • Cellular Localization
  • Secreted
  • Post Translation Modifications
  • N-terminal processed form MIP-1-beta(3-69) is produced by proteolytic cleavage after secretion from peripheral blood lymphocytes.
  • Function
  • Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

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Capture antibody

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Secondary Antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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