Recombinant Rabbit Anti-CCL4 Detection Antibody (clone R08-5V7) (CAT#: VS3-WK1793)
This antibody is a rabbit recombinant antibody against human CCL4. It was developed by immunization of rabbit with recombinant human CCL4 protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. R06-2O6 and R08-5V7 were identified as antibody pair for sandwich ELISA. As a detection antibody, the clone R08-5V7 can be used in ELISA analysis to identify human CCL4.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Normal Tissue
Figure 1 Cerebral cortex
(Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7805/22731_B_7_5.jpg
(Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7805/22731_B_7_5.jpg
Figure 2 Testis
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7805/22731_A_6_6.jpg
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7805/22731_A_6_6.jpg
Specifications
- Immunogen
- Recombinant human CCL4 protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human CCL4
- Species Reactivity
- Human
- Clone
- R08-5V7
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01M PBS, pH 7.2
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- C-C Motif Chemokine Ligand 4; Small Inducible Cytokine A4 (Homologous To Mouse Mip-1b); Macrophage Inflammatory Protein 1-Beta; Lymphocyte Activation Gene 1 Protein; G-26 T-Lymphocyte-Secreted Protein; Chemokine (C-C Motif) Ligand 4; T-Cell Activation Protein 2; MIP-1-Beta(1-69); MIP-1-Beta; SIS-Gamma; PAT 744; SCYA4; LAG-1; MIP1B
- Gene ID
- 6351
- UniProt ID
- P13236
- Long Name
- C-C Motif Chemokine Ligand 4
- Sequence Similarities
- Belongs to the intercrine beta (chemokine CC) family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- N-terminal processed form MIP-1-beta(3-69) is produced by proteolytic cleavage after secretion from peripheral blood lymphocytes.
- Protein Refseq
- NP_002975.1
- Function
- Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-386-sdAb | Recombinant Anti-Human CCL4 VHH Single Domain Antibody | IHC, IP, FC, Neut, FUNC | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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